日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large-scale F0 CRISPR screens in vivo using MIC-Drop

使用 MIC-Drop 进行大规模 F0 CRISPR 体内筛选

Saba Parvez, Zachary J Brandt, Randall T Peterson

Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish

Z-REX:引导活性亲电试剂靶向组织特异性或普遍表达的特定蛋白质,并记录幼鱼体内由此产生的亲电试剂诱导的功能性氧化还原反应。

Kuan-Ting Huang # ,Jesse R Poganik # ,Saba Parvez ,Sruthi Raja ,Brian Miller ,Marcus J C Long ,Joseph R Fetcho ,Yimon Aye

Z-REX uncovers a bifurcation in function of Keap1 paralogs

Z-REX 揭示了 Keap1 旁系同源基因的功能分岔

Alexandra Van Hall-Beauvais # ,Jesse R Poganik # ,Kuan-Ting Huang # ,Saba Parvez ,Yi Zhao ,Hong-Yu Lin ,Xuyu Liu ,Marcus John Curtis Long ,Yimon Aye

Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera

Wdr1 和 cofilin 是 Tecfidera 诱导的免疫细胞特异性凋亡所必需的介质。

Jesse R Poganik ,Kuan-Ting Huang ,Saba Parvez ,Yi Zhao ,Sruthi Raja ,Marcus J C Long ,Yimon Aye

Akt3 is a privileged first responder in isozyme-specific electrophile response

Akt3 是同工酶特异性亲电反应中具有特权的第一反应者

Marcus J C Long, Saba Parvez, Yi Zhao, Sanjna L Surya, Yiran Wang, Sheng Zhang, Yimon Aye

β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling

β-TrCP1 是 Wnt 信号传导的波动调节因子

Marcus John Long ,Hong-Yu Lin ,Saba Parvez ,Yi Zhao ,Jesse Richard Poganik ,Paul Huang ,Yimon Aye

T-REX on-demand redox targeting in live cells

T-REX 在活细胞中按需进行氧化还原靶向

Saba Parvez ,Marcus J C Long ,Hong-Yu Lin ,Yi Zhao ,Joseph A Haegele ,Vanha N Pham ,Dustin K Lee ,Yimon Aye