A microbiota-derived bile acid overcomes antibiotic-induced hyporesponsiveness to immune checkpoint therapy by enhancing CD8 (+) T cell antitumor immunity
肠道菌群来源的胆汁酸可通过增强 CD8(+) T 细胞抗肿瘤免疫力来克服抗生素引起的免疫检查点疗法低反应性。
期刊:
影响因子:
doi:10.64898/2026.04.15.718788
Li, Wenling; Zarek, Christina M; Wang, Hesuiyuan; Gan, Shuheng; Sabaiefard, Parastoo; Del Valle, Priscilla; Kim, Jiwoong; Poulides, Nicole; Coughlin, Laura A; Lichterman, Jake N; Zhang, Cheng; Chiu, Rebecca Suet-Yan; Srinivasan, Tarun; Velasquez, Mauricio J; Raman, Indu; Maddox, Vanessa J; McDonald, Jeffrey; Kittler, Ralf; Raj, Prithvi; Li, Xin V; Zhan, Xiaowei; Liao, Chen; Xavier, Joao B; Koh, Andrew Y
微生物学
CD8
免疫/内分泌
细胞生物学
肠道菌群
肿瘤
肿瘤免疫
T细胞
