WBP2 Attenuates Metformin Response in HER2-Positive Breast Cancer Cells by Repressing AMPK Activation and Inducing a Lower AMP:ATP Ratio State Through Enhanced ATP Production
WBP2通过抑制AMPK激活并增强ATP生成,诱导较低的AMP/ATP比值,从而减弱HER2阳性乳腺癌细胞对二甲双胍的反应。
期刊:Cells
影响因子:5.2
doi:10.3390/cells15040381
Lin, Hexian; Kang, Shin-Ae; Xie, Fei; Lim, Yvonne Xinyi; Seah, Sock Hong; Sabbaghian, Amir; Lu, Ssu-Yi; Chew, Ting Gang; Deng, Lih-Wen; Wang, Shu; Tai, E-Shyong; Lim, Yoon Pin