Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice
FBXO7(PARK15)的缺失会导致蛋白酶体活性降低,并在小鼠中模拟出类似帕金森病的表型
期刊:EMBO Journal
影响因子:9.4
doi:10.15252/embj.201593585
Siv Vingill, David Brockelt, Camille Lancelin, Lars Tatenhorst, Guergana Dontcheva, Christian Preisinger, Nicola Schwedhelm-Domeyer, Sabitha Joseph, Miso Mitkovski, Sandra Goebbels, Klaus-Armin Nave, Jörg B Schulz, Till Marquardt, Paul Lingor, Judith Stegmüller