Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice
从1型糖尿病患者体内克隆的胰岛特异性CTL在移植到HLA-A2转基因NOD/scid/IL2RG基因敲除小鼠体内后，可导致β细胞破坏。
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0049213
Unger, Wendy W J; Pearson, Todd; Abreu, Joana R F; Laban, Sandra; van der Slik, Arno R; der Kracht, Sacha Mulder-van; Kester, Michel G D; Serreze, Dave V; Shultz, Leonard D; Griffioen, Marieke; Drijfhout, Jan Wouter; Greiner, Dale L; Roep, Bart O
