日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CD40L-adjuvanted DNA/modified vaccinia virus Ankara simian immunodeficiency virus (SIV) vaccine enhances protection against neutralization-resistant mucosal SIV infection

CD40L佐剂DNA/改良痘苗病毒安卡拉猴免疫缺陷病毒(SIV)疫苗可增强对耐中和性黏膜SIV感染的保护作用

Kwa, Suefen; Sadagopal, Shanmugalakshmi; Shen, Xiaoying; Hong, Jung Joo; Gangadhara, Sailaja; Basu, Rahul; Victor, Blandine; Iyer, Smita S; LaBranche, Celia C; Montefiori, David C; Tomaras, Georgia D; Villinger, Francois; Moss, Bernard; Kozlowski, Pamela A; Amara, Rama Rao

Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates

疫苗诱导产生的针对猴免疫缺陷病毒SIVmac239包膜的线性表位特异性抗体与非人灵长类动物体内针对人类免疫缺陷病毒1型包膜的抗体不同。

Shen, Xiaoying; Duffy, Ryan; Howington, Robert; Cope, Alethea; Sadagopal, Shanmugalakshmi; Park, Haesun; Pal, Ranajit; Kwa, Suefen; Ding, Song; Yang, Otto O; Fouda, Genevieve G; Le Grand, Roger; Bolton, Diane; Esteban, Mariano; Phogat, Sanjay; Roederer, Mario; Amara, Rama R; Picker, Louis J; Seder, Robert A; McElrath, M Juliana; Barnett, Susan; Permar, Sallie R; Shattock, Robin; DeVico, Anthony L; Felber, Barbara K; Pavlakis, George N; Pantaleo, Giuseppe; Korber, Bette T; Montefiori, David C; Tomaras, Georgia D

Diminished viral control during simian immunodeficiency virus infection is associated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa

猿猴免疫缺陷病毒感染期间病毒控制能力下降与直肠粘膜淋巴滤泡中 PD-1hi CD4 T 细胞异常富集有关

Geetha H Mylvaganam, Vijayakumar Velu, Jung-Joo Hong, Shanmugalakshmi Sadagopal, Suefen Kwa, Rahul Basu, Benton Lawson, Francois Villinger, Rama Rao Amara

B cell responses to HIV antigen are a potent correlate of viremia in HIV-1 infection and improve with PD-1 blockade

细胞对 HIV 抗原的反应是 HIV-1 感染中病毒血症的有力相关因素,可通过 PD-1 阻断得到改善

Katherine J Nicholas, Emily K Zern, Louise Barnett, Rita M Smith, Shelly L Lorey, Courtney A Copeland, Shanmugalakshmi Sadagopal, Spyros A Kalams

Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity

HIV 特异性 T 细胞反应中的主要克隆型为程序性死亡-1high 和 CD127low,且表现出较低的变体交叉反应性

Joseph A Conrad, Ramesh K Ramalingam, Rita M Smith, Louise Barnett, Shelly L Lorey, Jie Wei, Brenna C Simons, Shanmugalakshmi Sadagopal, Dirk Meyer-Olson, Spyros A Kalams

The genetic structure of south Asian populations as revealed by 650 000 SNPs

通过65万个SNP揭示的南亚人群的遗传结构

Shivaji, Sisinthy; Ara, Sreenivas; Bandi, Sunil; Singh, Aditya; Kumar Pinnaka, Anil; Metspalu, Mait; Chaubey, Gyaneshwer; Yunusbayev, Bayazit; Romero, Irene Gallego; Karmin, Monika; Mallick, Chandana Basu; Metspalu, Ene; Shanmugalakshmi, Sadagopal; Balakrishnan, Karuppiah; Thangaraj, Kumarasamy; Singh, Lalji; Pitchappan, Ramasamy; Kivisild, Toomas; Villems, Richard

Reducing the activity and secretion of microbial antioxidants enhances the immunogenicity of BCG

降低微生物抗氧化剂的活性和分泌可增强卡介苗的免疫原性。

Sadagopal, Shanmugalakshmi; Braunstein, Miriam; Hager, Cynthia C; Wei, Jie; Daniel, Alexandria K; Bochan, Markian R; Crozier, Ian; Smith, Nathaniel E; Gates, Hiriam O; Barnett, Louise; Van Kaer, Luc; Price, James O; Blackwell, Timothy S; Kalams, Spyros A; Kernodle, Douglas S

Enhancement of human immunodeficiency virus (HIV)-specific CD8+ T cells in cerebrospinal fluid compared to those in blood among antiretroviral therapy-naive HIV-positive subjects.

与未接受抗逆转录病毒治疗的 HIV 阳性受试者的血液相比,脑脊液中人类免疫缺陷病毒 (HIV) 特异性 CD8+ T 细胞有所增强

Sadagopal Shanmugalakshmi, Lorey Shelly L, Barnett Louise, Basham Rebecca, Lebo Laurie, Erdem Husamettin, Haman Kirsten, Avison Malcolm, Waddell Kevin, Haas David W, Kalams Spyros A