日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity.

发现并表征了具有强大髓系激活和抗肿瘤活性的首创 LIV1-TLR7/8 免疫调节偶联物

Yamazoe Sayumi, Poudel Yam, Sega Emanuela, Mukhopadhyay Anandaroop, Ramakrishnan Radha, Ukairo Okechukwu, Liu Scot, Akter Rahima, Sadanala Keerthi, Que Kathryn, Cheng Qinqin, Kotapati Srikanth, Deshpande Madhura, Cox Matthew, Chourey Shishir, Gupta Anuradha, Kempson James, Pabbisetty Kumar, Kaspady Mahammed, Bhattasali Debabrata, Yip Shiuhang, Wu Dauh-Rurng, Pookot Deepa, Li Yvonne, Kozhich Alexander, Drexler Dieter, Carl Stephen, Deyanova Ekaterina, Smith Michael, Chan Henry, West Sean, Diong S J, Chang Aram, Florin Lore, Mathur Arvind, Strop Pavel, Zapf Christoph W, Law Deborah, Wilson Nicholas, Broz Miranda, Chekler Eugene P

Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells

将TLR7激动剂靶向递送至肿瘤微环境可通过激活肿瘤驻留髓系细胞增强肿瘤免疫力

Sega, Emanuela; Kotapati, Srikanth; Poudel, Yam B; Cheng, Qinqin; Sadanala, Keerthi; Schneider, Bridget; Chekler, Eugene P; Rao, Chetana; Gangwar, Sanjeev; Sproul, Tim; Law, Deborah; Broz, Miranda; Strop, Pavel; Yamazoe, Sayumi

Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling

人类膀胱癌中自然杀伤细胞功能障碍是由SLAMF6信号传导的组织特异性抑制引起的

Farkas, Adam M; Youssef, Dina; Tran, Michelle A; Balan, Sreekumar; Newman, Jenna H; Audenet, François; Anastos, Harry; Velazquez, Leandra G; Peros, Ante; Ananthanarayanan, Aparna; Daza, Jorge; Gonzalez-Gugel, Elena; Sadanala, Keerthi; Theorell, Jakob; Galsky, Matthew D; Horowitz, Amir; Sfakianos, John P; Bhardwaj, Nina