Novel series of tunable µOR modulators with enhanced brain penetration for the treatment of opioid use disorder, pain and neuropsychiatric indications
新型可调谐μOR调节剂系列,具有增强的脑穿透性,可用于治疗阿片类药物使用障碍、疼痛和神经精神疾病
期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2023.129405
Nerurkar, Alok; Nguyen, Thomas; Wang, Sheldon; Bhatt, Ulhas; Li, Kevin; Li, Yihong; Ding, Pingyu; Seidl, Frederick J; Holan, Martin; Lee, John; Widjaja, Tien; Wei, Zhi-Liang; Sadlowski, Corinne; Sperandio, David; McGee, Lawrence R; Youngblood, Beth; Schwartz, Neil; Gehlert, Donald; Medina, Julio C