日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.

利用时间分辨冷冻电镜观察细菌 RNA 聚合酶启动子熔解的早期中间体

Saecker Ruth M, Mueller Andreas U, Malone Brandon, Chen James, Budell William C, Dandey Venkata P, Maruthi Kashyap, Mendez Joshua H, Molina Nina, Eng Edward T, Yen Laura Y, Potter Clinton S, Carragher Bridget, Darst Seth A

Structural origins of Escherichia coli RNA polymerase open promoter complex stability

大肠杆菌RNA聚合酶开放启动子复合物稳定性的结构起源

Saecker, Ruth M; Chen, James; Chiu, Courtney E; Malone, Brandon; Sotiris, Johanna; Ebrahim, Mark; Yen, Laura Y; Eng, Edward T; Darst, Seth A

Transcription initiation in mycobacteria: a biophysical perspective

分枝杆菌的转录起始:生物物理学视角

Boyaci, Hande; Saecker, Ruth M; Campbell, Elizabeth A

Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA

分枝杆菌转录起始复合物及其必需调节因子RbpA的结构和功能

Hubin, Elizabeth A; Fay, Allison; Xu, Catherine; Bean, James M; Saecker, Ruth M; Glickman, Michael S; Darst, Seth A; Campbell, Elizabeth A

One-step DNA melting in the RNA polymerase cleft opens the initiation bubble to form an unstable open complex

RNA聚合酶裂隙中DNA的一步解链打开起始泡,形成不稳定的开放复合物。

Gries, Theodore J; Kontur, Wayne S; Capp, Michael W; Saecker, Ruth M; Record, M Thomas Jr

Probing DNA binding, DNA opening, and assembly of a downstream clamp/jaw in Escherichia coli RNA polymerase-lambdaP(R) promoter complexes using salt and the physiological anion glutamate

利用盐和生理阴离子谷氨酸探测大肠杆菌RNA聚合酶-λP(R)启动子复合物中DNA的结合、DNA的打开以及下游钳状/颚状结构的组装。

Kontur, Wayne S; Capp, Michael W; Gries, Theodore J; Saecker, Ruth M; Record, M Thomas Jr

Interactions of the osmolyte glycine betaine with molecular surfaces in water: thermodynamics, structural interpretation, and prediction of m-values

渗透调节剂甘氨酸甜菜碱与水中分子表面的相互作用:热力学、结构解释和m值预测

Capp, Michael W; Pegram, Laurel M; Saecker, Ruth M; Kratz, Megan; Riccardi, Demian; Wendorff, Timothy; Cannon, Jonathan G; Record, M Thomas Jr