日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Ni(II) Chiral Square-Complex-Mediated Mannich Alkynylation for the Synthesis of Enantiomerically Enriched Unnatural α‑Amino Acids with Collagenase Inhibitory Activity

镍(II)手性方络合物介导的曼尼希炔基化反应合成具有胶原酶抑制活性的对映体富集的非天然α-氨基酸

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.6c00199
Grigoryan, Anna; Hayriyan, Liana; Gevorgyan, Hasmik; Sargsyan, Armen; Langer, Peter; Saghyan, Ashot; Mkrtchyan, Anna
发表日期：2026
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Ni(II) Chiral Square-Complex–Mediated Mannich Alkynylation for the Synthesis of Enantiomerically Enriched Unnatural α‑Amino Acids with Collagenase Inhibitory Activity

镍(II)手性方络合物介导的曼尼希炔基化反应合成具有胶原酶抑制活性的对映体富集的非天然α-氨基酸

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0305607
Hughes, Hunter P; Thompson, Diane; Foster, Gavin L; Lees, Jonathan; Surge, Donna; Standish, Christopher D; Grigoryan, Anna; Hayriyan, Liana; Gevorgyan, Hasmik; Sargsyan, Armen; Langer, Peter; Saghyan, Ashot; Mkrtchyan, Anna
发表日期：2026
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Binding of G-quadruplex DNA and serum albumins by synthetic non-proteinogenic amino acids: Implications for c-Myc-related anticancer activity and drug delivery

合成的非蛋白源氨基酸与G-四链体DNA和血清白蛋白的结合：对c-Myc相关抗癌活性和药物递送的意义

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102478
Simonyan, Hayarpi; Palumbo, Rosanna; Vicidomini, Caterina; Scognamiglio, Pasqualina Liana; Petrosyan, Satenik; Sahakyan, Lusine; Melikyan, Gagik; Saghyan, Ashot; Roviello, Giovanni N
肿瘤
肿瘤免疫
发表日期：2025
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Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against Aspergillus Species

Fmoc保护的1,2,4-三唑基-α-氨基酸及其二肽的合成及其对曲霉属真菌的抗真菌活性

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom15010061
Sargsyan, Tatevik; Stepanyan, Lala; Panosyan, Henrik; Hakobyan, Heghine; Israyelyan, Monika; Tsaturyan, Avetis; Hovhannisyan, Nelli; Vicidomini, Caterina; Mkrtchyan, Anna; Saghyan, Ashot; Roviello, Giovanni N
微生物学
发表日期：2025
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Sequential Michael addition, cross-coupling and [3 + 2] cycloaddition reactions within the coordination sphere of chiral Ni(ii) Schiff base complexes derived from dehydroamino acids: pathways to the asymmetric synthesis of structurally diverse O-substituted serine and threonine analogs

手性Ni(ii)席夫碱配合物（源自脱氢氨基酸）配位球内的连续迈克尔加成、交叉偶联和[3+2]环加成反应：不对称合成结构多样的O-取代丝氨酸和苏氨酸类似物的途径

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra00910c
Khachatryan, Emma A; Sahakyan, Lusine Yu; Tovmasyan, Anna S; Melikyan, Gagik S; Panosyan, Henrik A; Mkrtchyan, Anna F; Shibata, Norio; Malkov, Andrei V; Saghyan, Ashot S
发表日期：2025
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A(3)-Mannich coupling reaction via chiral propargylglycine Ni(ii) complex: an approach for synthesizing enantiomerically enriched unnatural α-amino acids

通过手性炔丙基甘氨酸镍(II)络合物进行的A(3)-曼尼希偶联反应：一种合成对映体富集的非天然α-氨基酸的方法

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra04554a
Hayriyan, Liana; Grigoryan, Anna; Gevorgyan, Hasmik; Tsaturyan, Avetis; Sargsyan, Armen; Langer, Peter; Saghyan, Ashot; Mkrtchyan, Anna
发表日期：2025
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Synthesis and Biological Activity of Ultrashort Antimicrobial Peptides Bearing a Non-Coded Amino Acid

含非编码氨基酸的超短抗菌肽的合成及生物活性

期刊:Journal of Peptide Science
影响因子:1.8
doi:10.1002/psc.70021
Peggion, Cristina; Schivo, Andrea; Rotondo, Martina; Oancea, Simona; Popovici, Lucia-Florina; Călin, Teodora; Mkrtchyan, Anna; Saghyan, Ashot; Hayriyan, Liana; Khachatryan, Emma; Formaggio, Fernando; Biondi, Barbara
发表日期：2025
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BSA Binding and Aggregate Formation of a Synthetic Amino Acid with Potential for Promoting Fibroblast Proliferation: An In Silico, CD Spectroscopic, DLS, and Cellular Study

一种具有促进成纤维细胞增殖潜力的合成氨基酸与牛血清白蛋白（BSA）结合及聚集体形成的研究：计算机模拟、圆二色谱、动态光散射和细胞实验研究

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom14050579
Simonyan, Hayarpi; Palumbo, Rosanna; Petrosyan, Satenik; Mkrtchyan, Anna; Galstyan, Armen; Saghyan, Ashot; Scognamiglio, Pasqualina Liana; Vicidomini, Caterina; Fik-Jaskólka, Marta; Roviello, Giovanni N
成纤维细胞
细胞生物学
发表日期：2024
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Synthesis of enantiomerically enriched β-substituted analogs of (S)-α-alanine containing 1-phenyl-1H-1,2,3-triazole groups

合成含1-苯基-1H-1,2,3-三唑基团的(S)-α-丙氨酸对映体富集的β-取代类似物

期刊:Amino Acids
影响因子:2.4
doi:10.1007/s00726-024-03430-5
Poghosyan, Artavazd S; Khachatryan, Emma A; Mkrtchyan, Anna F; Mirzoyan, Volodya; Hovhannisyan, Anahit M; Ghazaryan, Karapet R; Minasyan, Ela V; Langer, Peter; Saghyan, Ashot S
发表日期：2024
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Synthesis, Characterization, and Study of Catalytic Activity of Chiral Cu(II) and Ni(II) Salen Complexes in the α-Amino Acid C-α Alkylation Reaction

手性Cu(II)和Ni(II) Salen配合物的合成、表征及其在α-氨基酸C-α烷基化反应中的催化活性研究

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules28031180
Tovmasyan, Anna S; Mkrtchyan, Anna F; Khachatryan, Hamlet N; Hayrapetyan, Mary V; Hakobyan, Robert M; Poghosyan, Artavazd S; Tsaturyan, Avetis H; Minasyan, Ela V; Maleev, Victor I; Larionov, Vladimir A; Ayvazyan, Armen G; Shibata, Norio; Roviello, Giovanni N; Saghyan, Ashot S
发表日期：2023
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