日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila

去泛素化酶USP47通过拮抗N端规则连接酶POE/UBR4的功能来稳定果蝇中的MAPK

Ashton-Beaucage, Dariel; Lemieux, Caroline; Udell, Christian M; Sahmi, Malha; Rochette, Samuel; Therrien, Marc

A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila.

功能筛选揭示了果蝇 RAS/MAPK 信号传导中广泛的转录和剪接控制机制

Ashton-Beaucage Dariel, Udell Christian M, Gendron Patrick, Sahmi Malha, Lefrançois Martin, Baril Caroline, Guenier Anne-Sophie, Duchaine Jean, Lamarre Daniel, Lemieux Sébastien, Therrien Marc

A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila

HYP(一种新型的含SAM结构域的蛋白质)介导的KSR/CNK复合物调节果蝇中RAS依赖的RAF激活。

Douziech, Mélanie; Sahmi, Malha; Laberge, Gino; Therrien, Marc