日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma.

从头合成丝氨酸是一种代谢弱点,可以利用这种弱点来克服晚期肾细胞癌的舒尼替尼耐药性

Teisseire Manon, Sahu Umakant, Parola Julien, Tsai Meng-Chen, Vial Valérie, Durivault Jérôme, Grépin Renaud, Cormerais Yann, Molina Clément, Gouraud Arthur, Pagès Gilles, Ben-Sahra Issam, Giuliano Sandy

Succinate dehydrogenase activity supports de novo purine synthesis.

琥珀酸脱氢酶活性支持嘌呤的从头合成

Nengroo Mushtaq A, Klein Austin T, Carr Heather S, Vidal-Cruchez Olivia, Sahu Umakant, McGrail Daniel J, Sahni Nidhi, Gao Peng, Asara John M, Shah Hardik, Mendillo Marc L, Ben-Sahra Issam

Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis

嘧啶维持线粒体丙酮酸氧化,以支持从头脂肪生成。

Sahu, Umakant; Villa, Elodie; Reczek, Colleen R; Zhao, Zibo; O'Hara, Brendan P; Torno, Michael D; Mishra, Rohan; Shannon, William D; Asara, John M; Gao, Peng; Shilatifard, Ali; Chandel, Navdeep S; Ben-Sahra, Issam

GATOR2 rings GATOR1 to speak to mTORC1

GATOR2 呼叫 GATOR1 以与 mTORC1 通信。

Sahu, Umakant; Ben-Sahra, Issam

Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides

癌细胞通过调节信号通路来增强核苷酸的从头合成。

Villa, Elodie; Ali, Eunus S; Sahu, Umakant; Ben-Sahra, Issam