日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Implications of the FDA's new plausible mechanism framework for the development of a personalized in vivo prime editing platform

FDA新的合理机制框架对开发个性化体内先导基因编辑平台的影响

期刊:American Journal of Human Genetics
影响因子:8.1
doi:10.1016/j.ajhg.2026.03.018
Feierman, Emily R; Whittaker, Madelynn N; Quigley, Aidan; Brooks, Dominique L; McVeigh, Paige; Nan, Angela X; Hsu, Alvin; Said, Hooda; Soliman, Ousamah Younoss; Giovenco, Ryan; Davidson, Beverly L; Alameh, Mohamad-Gabriel; Liu, David R; Wang, Xiao; Musunuru, Kiran; Ahrens-Nicklas, Rebecca C
发表日期：2026
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Correction of a recurrent pathogenic variant in methylmalonic acidemia using adenine base editing

利用腺嘌呤碱基编辑技术纠正甲基丙二酸血症中的复发性致病变异

期刊:
影响因子:
doi:10.64898/2026.03.12.711365
Kahn, Elena M; Said, Hooda; Qu, Ping; Alameh, Mohamad-Gabriel; Wang, Xiao; Musunuru, Kiran; Ahrens-Nicklas, Rebecca C
碱基编辑
发表日期：2026
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Liver-directed base editing of ABCC6 prevents ectopic calcification in a variant-humanized mouse model of pseudoxanthoma elasticum.

针对肝脏的 ABCC6 碱基编辑可防止假性黄色瘤人源化小鼠模型中的异位钙化。

期刊:Molecular Therapy-Nucleic Acids
影响因子:6.1
doi:10.1016/j.omtn.2025.102769
Testa Lauren C, Obiri-Yeboah Dora, Said Hooda, Qu Ping, Levine Michael A, Alameh Mohamad-Gabriel, Musunuru Kiran, Li Qiaoli, Wang Xiao
肝癌
Human
Mouse
肿瘤
碱基编辑
发表日期：2025
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Systemic mRNA-LNP administration in fetuses improves survival in a mouse model of spinal muscular atrophy.

在脊髓性肌萎缩症小鼠模型中，对胎儿进行全身性 mRNA-LNP 给药可提高存活率。

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2025.101599
Carpenter Marco D, Kus Nicole, Choi Rosa B, Said Hooda, Dumitru Ana Maria, Bauer Jackson H, Wang Samantha, Luks Valerie, Teerdhala Sriya, Shah Aarsha, Zoltick Philip W, Alameh Mohamad G, Peranteau William
肌萎缩症
Mouse
发表日期：2025
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Pre-Vaccination Immune Profiles and Responsiveness to Innate Stimuli Predict Reactogenicity and Antibody Magnitude Following mRNA Vaccination.

接种疫苗前的免疫特征和对先天刺激的反应性可预测 mRNA 疫苗接种后的反应原性和抗体水平

期刊:Vaccines
影响因子:3.4
doi:10.3390/vaccines13070718
Zelkoski Amanda E, Goguet Emilie, Samuels Darcey Emily, Alameh Mohamad-Gabriel, Said Hooda, Pollett Simon, Powers John H 3rd, Laing Eric D, Olsen Cara, Mitre Edward, Malloy Allison M W
免疫/内分泌
发表日期：2025
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A base editing strategy using mRNA-LNPs for in vivo correction of the most frequent phenylketonuria variant

利用mRNA-LNP进行碱基编辑的策略，用于体内纠正最常见的苯丙酮尿症变异体

期刊:HGG Advances
影响因子:3.6
doi:10.1016/j.xhgg.2023.100253
Brooks, Dominique L; Whittaker, Madelynn N; Said, Hooda; Dwivedi, Garima; Qu, Ping; Musunuru, Kiran; Ahrens-Nicklas, Rebecca C; Alameh, Mohamad-Gabriel; Wang, Xiao
碱基编辑
发表日期：2024
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Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration

mRNA脂质纳米粒子的电离和结构特性会影响肌内注射和血管内给药后的表达。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-021-02441-2
Carrasco, Manuel J; Alishetty, Suman; Alameh, Mohamad-Gabriel; Said, Hooda; Wright, Lacey; Paige, Mikell; Soliman, Ousamah; Weissman, Drew; Cleveland, Thomas E 4th; Grishaev, Alexander; Buschmann, Michael D
发表日期：2021
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