日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MK-2206, an Akt inhibitor, enhances carboplatinum/paclitaxel efficacy in gastric cancer cell lines

Akt 抑制剂 MK-2206 可增强卡铂/紫杉醇对胃癌细胞系的疗效

Khaldoun Almhanna, Christopher L Cubitt, Shumin Zhang, Sabiha Kazim, Kazim Husain, Daniel Sullivan, Said Sebti, Mokenge Malafa

Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation

发现马里诺吡咯 A (maritoclax) 是一种选择性 Mcl-1 拮抗剂,可通过结合并靶向 Mcl-1 进行蛋白酶体降解来克服 ABT-737 耐药性

Kenichiro Doi, Rongshi Li, Shen-Shu Sung, Hongwei Wu, Yan Liu, Wanda Manieri, Gowdahalli Krishnegowda, Andy Awwad, Alden Dewey, Xin Liu, Shantu Amin, Chunwei Cheng, Yong Qin, Ernst Schonbrunn, Gary Daughdrill, Thomas P Loughran Jr, Said Sebti, Hong-Gang Wang

TNF-α-mediated proliferation of vascular smooth muscle cells involves Raf-1-mediated inactivation of Rb and transcription of E2F1-regulated genes

TNF-α 介导的血管平滑肌细胞增殖涉及 Raf-1 介导的 Rb 失活和 E2F1 调节基因的转录

Rebecca Davis, Smitha Pillai, Nicholas Lawrence, Said Sebti, Srikumar P Chellappan