日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Wheat-Based Protein Slows Disease Progression in Pkd1 Knockout Mice

小麦蛋白可延缓Pkd1基因敲除小鼠的疾病进展

Sedaka, Randee; Huang, Jifeng; Yamaguchi, Shinobu; Hallit, Emily; Moran-Reyna, Aida; Hsu, Jung-Shan; Lovelady, Caleb; Fujihashi, Ayaka; Sako, Mohammad; Kasztan, Malgorzata; Benavides, Gloria; Wilson, Landon; Darley-Usmar, Victor; Barnes, Stephen; Saigusa, Takamitsu

Intestinal barrier function declines during polycystic kidney disease progression.

多囊肾病进展过程中肠道屏障功能下降

Sedaka Randee, Lovelady Caleb, Hallit Emily, Duyvestyn Branden, Shinde Sejal, Moran-Reyna Aida, Lee Goo, Yamaguchi Shinobu, Maynard Craig L, Saigusa Takamitsu

Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct

小鼠皮质集合管中原发性纤毛的缺失会导致多囊蛋白-2和TRPV4的表达增加,并出现非选择性阳离子通道。

Saigusa, Takamitsu; Yue, Qiang; Bunni, Marlene A; Bell, P Darwin; Eaton, Douglas C

Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model

抑制血管紧张素原合成可减轻 Pkd1 小鼠模型中的肾囊肿形成

Saigusa, Takamitsu; Dang, Yujing; Mullick, Adam E; Yeh, Steve T; Zile, Michael R; Baicu, Catalin F; Bell, P Darwin

Suppressing kidney angiotensinogen in blood pressure regulation

抑制肾脏血管紧张素原在血压调节中的作用

Saigusa, Takamitsu

Molecular pathways and therapies in autosomal-dominant polycystic kidney disease

常染色体显性多囊肾病的分子通路和治疗方法

Saigusa, Takamitsu; Bell, P Darwin

Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage

纤毛缺失导致的高血糖会加速囊肿形成并诱发肾损伤。

Sas, Kelli M; Yin, Hong; Fitzgibbon, Wayne R; Baicu, Catalin F; Zile, Michael R; Steele, Stacy L; Amria, May; Saigusa, Takamitsu; Funk, Jason; Bunni, Marlene A; Siegal, Gene P; Siroky, Brian J; Bissler, John J; Bell, P Darwin

Reciprocal effect of angiotensin II in collecting duct renin synthesis

血管紧张素II对集合管肾素合成的相互作用

Saigusa, Takamitsu