日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor

对人类κ阿片受体偏向性信号传导机制的结构和动力学研究

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-64882-1
Suno-Ikeda, Chiyo; Nishikawa, Ryo; Suzuki, Riko; Yokoi, Shun; Iwata, Seiya; Takai, Tomoyo; Ogura, Takaya; Hirose, Mika; Tokuda, Akihisa; Katamoto, Risako; Inoue, Akitoshi; Asai, Eri; Kise, Ryoji; Sugita, Yukihiko; Kato, Takayuki; Nagase, Hiroshi; Mitsutake, Ayori; Saitoh, Tsuyoshi; Katayama, Kota; Inoue, Asuka; Kandori, Hideki; Kobayashi, Takuya; Suno, Ryoji
信号转导
发表日期：2025
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Correction: Delta opioid receptor agonists activate PI3K-mTORC1 signaling in parvalbumin-positive interneurons in mouse infralimbic prefrontal cortex to exert acute antidepressant-like effects

更正：δ阿片受体激动剂激活小鼠前额叶皮层下边缘区表达小白蛋白的中间神经元中的PI3K-mTORC1信号通路，从而发挥急性抗抑郁样作用。

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-025-03046-5
Yoshioka, Toshinori; Yamada, Daisuke; Hagiwara, Akari; Kajino, Keita; Iio, Keita; Saitoh, Tsuyoshi; Nagase, Hiroshi; Saitoh, Akiyoshi
信号转导
mTOR
神经科学
ORC1
发表日期：2025
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Delta opioid receptor agonists activate PI3K-mTORC1 signaling in parvalbumin-positive interneurons in mouse infralimbic prefrontal cortex to exert acute antidepressant-lie effects.

Delta 阿片受体激动剂激活小鼠下边缘前额皮质中小白蛋白阳性中间神经元的 PI3K-mTORC1 信号传导，从而发挥急性抗抑郁作用

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-024-02814-z
Yoshioka Toshinori, Yamada Daisuke, Hagiwara Akari, Kajino Keita, Iio Keita, Saitoh Tsuyoshi, Nagase Hiroshi, Saitoh Akiyoshi
神经科学
抑郁症
mTOR
Mouse
发表日期：2025
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Rapid-Onset Therapeutic Effects of Delta Opioid Receptor Agonists on Depression-Like Behaviors Induced by Chronic Social Defeat Stress

δ阿片受体激动剂对慢性社会挫败应激诱发的抑郁样行为的快速起效治疗作用

期刊:Neuropsychopharmacology Reports
影响因子:1.5
doi:10.1002/npr2.70059
Tokuda, Akihisa; Nagumo, Yasuyuki; Kajino, Keita; Iio, Keita; Sakurai, Katsuyasu; Mizuno, Seiya; Saitoh, Akiyoshi; Saitoh, Tsuyoshi; Nagase, Hiroshi
信号转导
神经科学
发表日期：2025
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Selective C-N Bond Cleavage in Unstrained Pyrrolidines Enabled by Lewis Acid and Photoredox Catalysis

路易斯酸和光氧化还原催化实现无张力吡咯烷中选择性CN键断裂

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c13210
Aida, Kazuhiro; Hirao, Marina; Saitoh, Tsuyoshi; Yamamoto, Takashi; Einaga, Yasuaki; Ota, Eisuke; Yamaguchi, Junichiro
发表日期：2024
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The delta opioid receptor agonist KNT-127 relieves innate anxiety-like behavior in mice by suppressing transmission from the prelimbic cortex to basolateral amygdala

δ阿片受体激动剂KNT-127通过抑制前边缘皮层到基底外侧杏仁核的信号传递，缓解小鼠的先天性焦虑样行为。

期刊:Neuropsychopharmacology Reports
影响因子:1.5
doi:10.1002/npr2.12406
Kawaminami, Ayako; Yamada, Daisuke; Yoshioka, Toshinori; Hatakeyama, Azumi; Nishida, Moeno; Kajino, Keita; Saitoh, Tsuyoshi; Nagase, Hiroshi; Saitoh, Akiyoshi
信号转导
发表日期：2024
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Chemogenetic activation of G(12) signaling enhances adipose tissue browning

化学遗传学激活G(12)信号通路可增强脂肪组织褐变

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-023-01524-2
Ono, Yuki; Ito, Ryo; Arai, Kaito; Singh, Gurdeep; Saitoh, Tsuyoshi; Russell, Robert B; Raimondi, Francesco; Aoki, Junken; Sakai, Juro; Inoue, Asuka
信号转导
发表日期：2023
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Positive allosteric adenosine A(2A) receptor modulation suppresses insomnia associated with mania- and schizophrenia-like behaviors in mice

腺苷A(2A)受体的正向变构调节可抑制小鼠躁狂和精神分裂症样行为相关的失眠

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2023.1138666
Lin, Yang; Roy, Koustav; Ioka, Shuji; Otani, Rintaro; Amezawa, Mao; Ishikawa, Yukiko; Cherasse, Yoan; Kaushik, Mahesh K; Klewe-Nebenius, Daniela; Zhou, Li; Yanagisawa, Masashi; Oishi, Yo; Saitoh, Tsuyoshi; Lazarus, Michael
信号转导
精神分裂症
神经科学
发表日期：2023
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Electro-conversion of cumene into acetophenone using boron-doped diamond electrodes

利用硼掺杂金刚石电极将异丙苯电化学转化为苯乙酮

期刊:Beilstein Journal of Organic Chemistry
影响因子:2.1
doi:10.3762/bjoc.18.119
Kitano, Mana; Saitoh, Tsuyoshi; Nishiyama, Shigeru; Einaga, Yasuaki; Yamamoto, Takashi
发表日期：2022
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