Sajish Mathew相关文献与解析，生知库 | 链接生命科学的每一步

Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depletion.

酪氨酸和苯丙氨酸激活神经元 DNA 修复，但对整体转录表现出相反的作用，成年雌性小鼠对 TyrRS/YARS1 耗竭具有抵抗力

Jhanji Megha, Bhan Ashita, Arrowood Colin, Yakout Dina W, Shroff Ankit, McManus Danielle, Gifford Henrietta, Vacharasin Janay, Lizarraga Sofia B, Nazarko Taras Y, Mabb Angela M, Sajish Mathew

神经科学

发表日期：2025

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The intersection of inflammation and DNA damage as a novel axis underlying the pathogenesis of autism spectrum disorders

炎症与DNA损伤的交汇点是自闭症谱系障碍发病机制的一个新轴心

期刊:

影响因子:

doi:10.1101/2024.12.11.627854

Jhanji, Megha; Krall, Colleen L; Guevara, Alexis; Yoon, Brian; Sajish, Mathew; Boccuto, Luigi; Lizarraga, Sofia B

Towards resolving the enigma of the dichotomy of resveratrol: cis- and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation

为了解开白藜芦醇二元性之谜：顺式和反式白藜芦醇对TyrRS调控的PARP1激活具有相反的作用

期刊:Geroscience

影响因子:5.4

doi:10.1007/s11357-020-00295-w

Jhanji, Megha; Rao, Chintada Nageswara; Sajish, Mathew

Early-onset colorectal cancer: initial clues and current views

早发性结直肠癌：初步线索和当前观点

期刊:Nature Reviews Gastroenterology & Hepatology

影响因子:51

doi:10.1038/s41575-019-0253-4

Hofseth, Lorne J; Hebert, James R; Chanda, Anindya; Chen, Hexin; Love, Bryan L; Pena, Maria M; Murphy, E Angela; Sajish, Mathew; Sheth, Amit; Buckhaults, Phillip J; Berger, Franklin G

Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy

另一种稳定的构象可能导致蛋白质错误相互作用，从而将tRNA合成酶与周围神经病变联系起来。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkx455

Blocquel, David; Li, Sheng; Wei, Na; Daub, Herwin; Sajish, Mathew; Erfurth, Maria-Luise; Kooi, Grace; Zhou, Jiadong; Bai, Ge; Schimmel, Paul; Jordanova, Albena; Yang, Xiang-Lei

发表日期：2017

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Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Trp-tRNA合成酶将DNA-PKcs与PARP-1连接起来，从而连接IFN-γ和p53信号通路。

期刊:Nature Chemical Biology

影响因子:13.7

doi:10.1038/nchembio.937

Sajish, Mathew; Zhou, Quansheng; Kishi, Shuji; Valdez, Delgado M Jr; Kapoor, Mili; Guo, Min; Lee, Sunhee; Kim, Sunghoon; Yang, Xiang-Lei; Schimmel, Paul

Orchestrating Neural Development Through mRNA Translation Regulation

通过mRNA翻译调控来协调神经发育

Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depletion.

酪氨酸和苯丙氨酸激活神经元 DNA 修复，但对整体转录表现出相反的作用，成年雌性小鼠对 TyrRS/YARS1 耗竭具有抵抗力

The intersection of inflammation and DNA damage as a novel axis underlying the pathogenesis of autism spectrum disorders

炎症与DNA损伤的交汇点是自闭症谱系障碍发病机制的一个新轴心

Towards resolving the enigma of the dichotomy of resveratrol: cis- and trans-resveratrol have opposite effects on TyrRS-regulated PARP1 activation

为了解开白藜芦醇二元性之谜：顺式和反式白藜芦醇对TyrRS调控的PARP1激活具有相反的作用

Early-onset colorectal cancer: initial clues and current views

早发性结直肠癌：初步线索和当前观点

Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy

另一种稳定的构象可能导致蛋白质错误相互作用，从而将tRNA合成酶与周围神经病变联系起来。

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling

Trp-tRNA合成酶将DNA-PKcs与PARP-1连接起来，从而连接IFN-γ和p53信号通路。