LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradation.
LYMTACs:嵌合小分子可重新利用溶酶体膜蛋白,实现靶蛋白的重新定位和降解
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63128-4
Nalawansha Dhanusha A, Mazis Georgios, Husemoen Gitte, Ashton Kate S, Deng Weixian, Wurz Ryan P, Tran Anh T, Lanman Brian A, Xie Jiansong, Guenette Robert G, Li Shiqian, Smith Christopher E, Archunan Suresh, Agnihotram Manoj K, Sadhukhan Arghya, Kapoor Rajiv, Wilde Chris, Koirala Sajjan, De Sousa E Melo Felipe, Potts Patrick Ryan