日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA

帕金森病药物托卡朋及其类似物是铜绿假单胞菌LecA的强效糖模拟凝集素抑制剂。

Leusmann, Steffen; Siebs, Eike; Kuhaudomlarp, Sakonwan; Varrot, Annabelle; Imberty, Anne; Kuhn, Bernd; Lerner, Christian; Grether, Uwe; Titz, Alexander

Metabolic insights into the warfarin-mango interaction: A pilot study integrating clinical observations and metabolomics

华法林与芒果相互作用的代谢机制研究:一项整合临床观察和代谢组学的初步研究

Rattanasuwan, Piyapat; Lertpongpipat, Prem; Hiranchatchawal, Natthapat; Wannaphueak, Konwalin; Pounghom, Sakonwan; Thongkhao-On, Parinya; Suwanthai, Matchuda; Sompradee, Duangthip; Saithongdee, Auiporn; Jaikang, Churdsak; Tajai, Preechaya

Discovery of C-12 dithiocarbamate andrographolide analogue as a novel antioxidant and α-glucosidase inhibitors: In vitro and in silico studies

发现C-12二硫代氨基甲酸酯穿心莲内酯类似物作为新型抗氧化剂和α-葡萄糖苷酶抑制剂:体外和计算机模拟研究

Suriya, Utid; Duangtha, Chanathip; Dontricharoen, Thanchanok; Yamanont, Paveena; Kuhaudomlarp, Sakonwan; Thitiyanuwat, Prawit; Nutho, Bodee; Arsakhant, Patcharee; Saeeng, Rungnapha; Morales, Noppawan Phumala; Mangmool, Supachoke; Likitnukul, Sutharinee

Safety evaluation of a novel effervescent curcumin-ascorbic acid-polysaccharide-β-cyclodextrin inclusion complex: Acute oral toxicity - fixed dose procedure (OECD TG 420) in mice

新型泡腾姜黄素-抗坏血酸-多糖-β-环糊精包合物的安全性评价:小鼠急性口服毒性固定剂量法(OECD TG 420)

Wanta, Arunothai; Aluksanasuwan, Siripat; Charoensup, Rawiwan; Jaidee, Wuttichai; Pramvichai, Chanatip; Saengnoy, Kritsada; Pongpakit, Daranrat; Jindarak, Sakonwan; Khamchan, Aree; Ariyawan, Wilasinee; Praserthsee, Wanlapa; Morchang, Atthapan; Rongjumnong, Artitaya; Somsuan, Keerakarn

High-Affinity Lectin Ligands Enable the Detection of Pathogenic Pseudomonas aeruginosa Biofilms: Implications for Diagnostics and Therapy

高亲和力凝集素配体可用于检测致病性铜绿假单胞菌生物膜:对诊断和治疗的意义

Zahorska, Eva; Denig, Lisa Marie; Lienenklaus, Stefan; Kuhaudomlarp, Sakonwan; Tschernig, Thomas; Lipp, Peter; Munder, Antje; Gillon, Emilie; Minervini, Saverio; Verkhova, Varvara; Imberty, Anne; Wagner, Stefanie; Titz, Alexander

Repurposing FDA-approved drugs targeting FZD10 in nasopharyngeal carcinoma: insights from molecular dynamics simulations and experimental validation

利用 FDA 批准的靶向 FZD10 的药物治疗鼻咽癌:来自分子动力学模拟和实验验证的启示

Ngernsombat, Chawalit; Suriya, Utid; Prattapong, Pongphol; Verma, Kanika; Rungrotmongkol, Thanyada; Soonkum, Thananya; Kuhaudomlarp, Sakonwan; Janvilisri, Tavan

Neutralizing the Impact of the Virulence Factor LecA from Pseudomonas aeruginosa on Human Cells with New Glycomimetic Inhibitors

利用新型糖模拟抑制剂中和铜绿假单胞菌毒力因子LecA对人类细胞的影响

Zahorska, Eva; Rosato, Francesca; Stober, Kai; Kuhaudomlarp, Sakonwan; Meiers, Joscha; Hauck, Dirk; Reith, Dorina; Gillon, Emilie; Rox, Katharina; Imberty, Anne; Römer, Winfried; Titz, Alexander

Bridging the Gap: Can COVID-19 Research Help Combat African Swine Fever?

弥合差距:COVID-19 研究能否帮助对抗非洲猪瘟?

Pakotiprapha, Danaya; Kuhaudomlarp, Sakonwan; Tinikul, Ruchanok; Chanarat, Sittinan

Druggable Allosteric Sites in β-Propeller Lectins

β-螺旋桨凝集素中的可成药变构位点

Shanina, Elena; Kuhaudomlarp, Sakonwan; Lal, Kanhaya; Seeberger, Peter H; Imberty, Anne; Rademacher, Christoph

Targeting undruggable carbohydrate recognition sites through focused fragment library design

通过聚焦片段库设计,靶向不可成药的碳水化合物识别位点

Elena Shanina, Sakonwan Kuhaudomlarp, Eike Siebs, Felix F Fuchsberger, Maxime Denis, Priscila da Silva Figueiredo Celestino Gomes, Mads H Clausen, Peter H Seeberger, Didier Rognan, Alexander Titz, Anne Imberty, Christoph Rademacher