Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform.

G12/13-Rho 和 Gi 通路整合于单个 G 蛋白偶联鞘氨醇-1-磷酸受体亚型的下游，对 Rac 和细胞运动进行抑制和刺激调节