日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

NI-3201 Is a Bispecific Antibody Mediating PD-L1-Dependent CD28 Co-stimulation on T Cells for Enhanced Tumor Control

NI-3201 是一种双特异性抗体,可介导 T 细胞上 PD-L1 依赖的 CD28 共刺激,从而增强肿瘤控制能力。

Sara Majocchi ,Pauline Lloveras ,Lise Nouveau ,Margaux Legrand ,Alizee Viandier ,Pauline Malinge ,Maud Charreton ,Cecile Raymond ,Emily A Pace ,Bjorn L Millard ,L Anders Svensson ,Vinardas Kelpšas ,Nadia Anceriz ,Susana Salgado-Pires ,Bruno Daubeuf ,Giovanni Magistrelli ,Franck Gueneau ,Valéry Moine ,Krzysztof Masternak ,Limin Shang ,Nicolas Fischer ,Walter G Ferlin

Targeting CEACAM5-positive solid tumors using NILK-2401, a novel CEACAM5xCD47 κλ bispecific antibody

利用新型CEACAM5xCD47 κλ双特异性抗体NILK-2401靶向CEACAM5阳性实体瘤

Seckinger, Anja; Buatois, Vanessa; Moine, Valéry; Daubeuf, Bruno; Richard, Françoise; Chatel, Laurence; Viandier, Alizée; Bosson, Nicolas; Rousset, Emeline; Masternak, Krzysztof; Salgado-Pires, Susana; Batista, Claudia; Mougin, Christelle; Juan-Bégeot, Flora; Poitevin, Yves; Hose, Dirk

Development and characterization of NILK-2301, a novel CEACAM5xCD3 κλ bispecific antibody for immunotherapy of CEACAM5-expressing cancers

NILK-2301 的开发和表征,一种用于 CEACAM5 表达癌症免疫治疗的新型 CEACAM5xCD3 κλ 双特异性抗体

Anja Seckinger #, Sara Majocchi #, Valéry Moine, Lise Nouveau, Hoang Ngoc, Bruno Daubeuf, Ulla Ravn, Nicolas Pleche, Sebastien Calloud, Lucile Broyer, Laura Cons, Adeline Lesnier, Laurence Chatel, Anne Papaioannou, Susana Salgado-Pires, Sebastian Krämer, Ines Gockel, Florian Lordick, Krzysztof Maste

Preclinical Development of a Bispecific Antibody that Safely and Effectively Targets CD19 and CD47 for the Treatment of B-Cell Lymphoma and Leukemia

用于治疗B细胞淋巴瘤和白血病的、安全有效靶向CD19和CD47的双特异性抗体的临床前开发

Vanessa Buatois # ,Zoë Johnson # ,Susana Salgado-Pires ,Anne Papaioannou ,Eric Hatterer ,Xavier Chauchet ,Françoise Richard ,Leticia Barba ,Bruno Daubeuf ,Laura Cons ,Lucile Broyer ,Matilde D'Asaro ,Thomas Matthes ,Simon LeGallou ,Thierry Fest ,Karin Tarte ,Robert K Clarke Hinojosa ,Eulàlia Genescà Ferrer ,José María Ribera ,Aditi Dey ,Katharine Bailey ,Adele K Fielding ,Linda Eissenberg ,Julie Ritchey ,Michael Rettig ,John F DiPersio ,Marie H Kosco-Vilbois ,Krzysztof Masternak ,Nicolas Fischer ,Limin Shang ,Walter G Ferlin

Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies

双靶向双特异性抗体可选择性阻断普遍存在的检查点受体 CD47

Elie Dheilly, Valéry Moine, Lucile Broyer, Susana Salgado-Pires, Zoë Johnson, Anne Papaioannou, Laura Cons, Sébastien Calloud, Stefano Majocchi, Robert Nelson, François Rousseau, Walter Ferlin, Marie Kosco-Vilbois, Nicolas Fischer, Krzysztof Masternak

Toll-Like Receptor 4 on both Myeloid Cells and Dendritic Cells Is Required for Systemic Inflammation and Organ Damage after Hemorrhagic Shock with Tissue Trauma in Mice

小鼠组织创伤性出血性休克后,髓系细胞和树突状细胞上的 Toll 样受体 4 是全身炎症和器官损伤所必需的。

Zettel, Kent; Korff, Sebastian; Zamora, Ruben; Morelli, Adrian E; Darwiche, Sophie; Loughran, Patricia A; Elson, Greg; Shang, Limin; Salgado-Pires, Susana; Scott, Melanie J; Vodovotz, Yoram; Billiar, Timothy R

Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering

选择性抗体干预 Toll 样受体 4 激活通过 Fcγ 受体束缚

Limin Shang, Bruno Daubeuf, Martha Triantafilou, Robin Olden, Fabien Dépis, Anne-Catherine Raby, Suzanne Herren, Anaelle Dos Santos, Pauline Malinge, Irene Dunn-Siegrist, Sanae Benmkaddem, Antoine Geinoz, Giovanni Magistrelli, François Rousseau, Vanessa Buatois, Susana Salgado-Pires, Walter Reith, R