日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of an in situ CAR-T cell protocol through optical and PSMA-targeted PET imaging.

通过光学和PSMA靶向PET成像开发原位CAR-T细胞方案

Zhang Nisi, Seo Jai Woong, Robinson Elise, Rivera-Rodriguez Angelie, Wang James, Guo Yutong, Czerwinski Debra K, Kim Ha Rin, Tumbale Spencer K, Raie Marina N, Jan Basit L, Engudar Gokce, Sallets Adrienne, Minn Il, Pomper Martin G, Levy Ronald, Ferrara Katherine W

Nanoparticle-formulated mRNA encoding engineered multivalent SIRPα-Fc fusion proteins shows robust anti-cancer activity in preclinical models.

纳米颗粒制剂的 mRNA 编码工程化的多价 SIRPα-Fc 融合蛋白在临床前模型中显示出强大的抗癌活性

Lal Shruti, Sallets Adrienne, Bandi Srinivasa R, Adusumilli Gowrisudha, Liu Weiqun, Low Ray, Ferry Kimmy, MacDonough Chris, ElAzzouny Mahmoud, Haabeth Ole A W, McKinlay Colin J, Hsu Pei-Ken, Sharma Anushtha, Dhungel Pragyesh, Triplett Jenna, Leong Meredith, McCartney-Melstad Evan, Deutsch Samuel, Gunasekaran Kannan

NTX250: A Modular mRNA-Based Immunotherapy Platform for HPV-Associated Cancers with Broad Applicability.

NTX250:一种具有广泛适用性的模块化 mRNA 免疫治疗平台,用于治疗 HPV 相关癌症。

Leong Meredith L, Liu Weiqun, Fay Nicole, Da Silva Diane M, Li Ou, Rae Chris S, Sallets Adrienne, Prins Ruben, Frimannsson Daniel, McKinlay Colin, Low Ray, Fernandez Daniel J, Kannan Gunasekaran, Dhungel Pragyesh, Nath Sangeeta, Peck Nicole E, Webster Elizabeth R, Wen Ximiao, Sharma Anushtha, Lemmens Edward E, Deutsch Samuel, Kast W Martin, Haabeth Ole Audun W

Discovery of a Peptoid-Based Nanoparticle Platform for Therapeutic mRNA Delivery via Diverse Library Clustering and Structural Parametrization

通过多样化库聚类和结构参数化发现用于治疗性 mRNA 递送的基于肽的纳米颗粒平台

Elizabeth R Webster, Nicole E Peck, Juan Diego Echeverri, Shima Gholizadeh, Wei-Lun Tang, Rinette Woo, Anushtha Sharma, Weiqun Liu, Chris S Rae, Adrienne Sallets, Gowrisudha Adusumilli, Kannan Gunasekaran, Ole A W Haabeth, Meredith Leong, Ronald N Zuckermann, Samuel Deutsch, Colin J McKinlay

Lysine-Derived Charge-Altering Releasable Transporters: Targeted Delivery of mRNA and siRNA to the Lungs

赖氨酸衍生的电荷改变可释放转运蛋白:将mRNA和siRNA靶向递送至肺部

Blake, Timothy R; Haabeth, Ole A W; Sallets, Adrienne; McClellan, Rebecca L; Del Castillo, Trevor J; Vilches-Moure, Jose G; Ho, Wilson C; Wender, Paul A; Levy, Ronald; Waymouth, Robert M

Neoadjuvant Intratumoral Immunotherapy with TLR9 Activation and Anti-OX40 Antibody Eradicates Metastatic Cancer

TLR9 激活和抗 OX40 抗体的新辅助肿瘤内免疫治疗可根除转移性癌症

Wan Xing Hong #, Idit Sagiv-Barfi #, Debra K Czerwinski, Adrienne Sallets, Ronald Levy

An mRNA SARS-CoV-2 Vaccine Employing Charge-Altering Releasable Transporters with a TLR-9 Agonist Induces Neutralizing Antibodies and T Cell Memory

采用电荷改变可释放转运体和 TLR-9 激动剂的 mRNA SARS-CoV-2 疫苗可诱导中和抗体和 T 细胞记忆

Ole A W Haabeth, Julian J K Lohmeyer, Adrienne Sallets, Timothy R Blake, Idit Sagiv-Barfi, Debra K Czerwinski, Blaine McCarthy, Abigail E Powell, Paul A Wender, Robert M Waymouth, Ronald Levy

An mRNA SARS-CoV-2 vaccine employing Charge-Altering Releasable Transporters with a TLR-9 agonist induces neutralizing antibodies and T cell memory

一种采用电荷改变释放转运体和TLR-9激动剂的mRNA SARS-CoV-2疫苗可诱导中和抗体和T细胞记忆。

Haabeth, Ole A W; Lohmeyer, Julian J K; Sallets, Adrienne; Blake, Timothy R; Sagiv-Barfi, Idit; Czerwinski, Debra K; McCarthy, Blaine; Powell, Abigail E; Wender, Paul A; Waymouth, Robert M; Levy, Ronald

Enhancing immunotherapy of STING agonist for lymphoma in preclinical models

在临床前模型中增强 STING 激动剂对淋巴瘤的免疫治疗

Adrienne Sallets, Sophie Robinson, Adel Kardosh, Ronald Levy