日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Comparing the Altis RepliGut Organoid System to MDCK Monolayers in Predicting the Oral Absorption of Lenalidomide

比较 Altis RepliGut 类器官系统与 MDCK 单层细胞在预测来那度胺口服吸收方面的性能

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17091140
Hudson, Cole S; Cheong, Jonathan; Yu, Jesse; Chen, Eugene C; Salphati, Laurent; Durk, Matthew R; Lai, Benjamin; Samy, Karen
3D/类器官
细胞生物学
DCK
MDC
发表日期：2025
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Young sanctuary-living chimpanzees produce more communicative expressions with artificial objects than with natural objects

生活在保护区的幼年黑猩猩与人造物体互动时，比与自然物体互动时，能表达出更多富有交流性的表情。

期刊:Royal Society Open Science
影响因子:2.9
doi:10.1098/rsos.240632
Gibson, Violet; Taylor, Derry; Salphati, Sarah; Somogyi, Eszter; Nomikou, Iris; Davila-Ross, Marina
发表日期：2024
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Early Stage Preclinical Formulation Strategies to Alter the Pharmacokinetic Profile of Two Small Molecule Therapeutics

早期临床前配方策略可改变两种小分子治疗药物的药代动力学特征

期刊:Pharmaceuticals
影响因子:
doi:10.3390/ph17020179
Le An, Tom De Bruyn, Jodie Pang, Savita Ubhayakar, Laurent Salphati, Xing Zhang, Liling Liu, Ruina Li, Bryan Chan, Anwesha Dey, Elizabeth S Levy
发表日期：2024
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RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy

RTK依赖性诱导突变PI3Kα降解驱动GDC-0077（Inavolisib）疗效

期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-21-0072
Kyung W Song，Kyle A Edgar，Emily J Hanan，Marc Hafner，Jason Oeh，Mark Merchant，Deepak Sampath，Michelle A Nannini，Rebecca Hong，Lilian Phu，William F Forrest，Eric Stawiski，Stephen Schmidt，Nicholas Endres，Jane Guan，Jeffrey J Wallin，Jonathan Cheong，Emile G Plise，Gail D Lewis Phillips，Laurent Salphati，Timothy P Heffron，Alan G Olivero，Shiva Malek，Steven T Staben，Donald S Kirkpatrick，Anwesha Dey，Lori S Friedman
PI3K/Akt
发表日期：2022
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Structural basis for proton coupled cystine transport by cystinosin

胱氨酸蛋白酶介导的质子偶联胱氨酸转运的结构基础

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-022-32589-2
Löbel, Mark; Salphati, Sacha P; El Omari, Kamel; Wagner, Armin; Tucker, Stephen J; Parker, Joanne L; Newstead, Simon
发表日期：2022
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Growth-rate model predicts in vivo tumor response from in vitro data

生长速率模型可根据体外数据预测体内肿瘤反应

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12836
Diegmiller, Rocky; Salphati, Laurent; Alicke, Bruno; Wilson, Timothy R; Stout, Thomas J; Hafner, Marc
肿瘤
肿瘤免疫
发表日期：2022
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Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor

新型 IDO1 抑制剂纳伏莫德的绝对生物利用度和人体质量平衡研究

期刊:British Journal of Clinical Pharmacology
影响因子:3.1
doi:10.1111/bcp.13961
Shuguang Ma, Julia Suchomel, Evelyn Yanez, Edward Yost, Xiaorong Liang, Rui Zhu, Hoa Le, Nicholas Siebers, Lori Joas, Roland Morley, Stephanie Royer-Joo, Andrea Pirzkall, Laurent Salphati, Joseph A Ware, Kari M Morrissey
IDO
发表日期：2019
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Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors

吲哚胺2,3-双加氧酶1 (IDO1) 抑制剂navoximod (GDC-0919) 治疗复发性晚期实体瘤患者的Ia期研究

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1186/s40425-018-0351-9
Nayak-Kapoor, Asha; Hao, Zhonglin; Sadek, Ramses; Dobbins, Robin; Marshall, Lisa; Vahanian, Nicholas N; Jay Ramsey, W; Kennedy, Eugene; Mautino, Mario R; Link, Charles J; Lin, Ray S; Royer-Joo, Stephanie; Liang, Xiaorong; Salphati, Laurent; Morrissey, Kari M; Mahrus, Sami; McCall, Bruce; Pirzkall, Andrea; Munn, David H; Janik, John E; Khleif, Samir N
IDO
发表日期：2018
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Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study

酒精性和丙型肝炎肝硬化患者肝组织中 1 期和 2 期药物代谢酶的丰富程度：定量靶向蛋白质组学研究

期刊:Drug Metabolism and Disposition
影响因子:4.4
doi:10.1124/dmd.118.080523
Bhagwat Prasad, Deepak Kumar Bhatt, Katherine Johnson, Revathi Chapa, Xiaoyan Chu, Laurent Salphati, Guangqing Xiao, Caroline Lee, Cornelis E C A Hop, Anita Mathias, Yurong Lai, Mingxiang Liao, William G Humphreys, Sean C Kumer, Jashvant D Unadkat
代谢
肝炎
发表日期：2018
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Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics

利用液相色谱-串联质谱蛋白质组学定量分析肝细胞癌和慢性丙型肝炎感染供体非癌性和癌性肝组织中转运蛋白的表达

期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1124/dmd.117.077289
Billington, Sarah; Ray, Adrian S; Salphati, Laurent; Xiao, Guangqing; Chu, Xiaoyan; Humphreys, W Griffith; Liao, Mingxiang; Lee, Caroline A; Mathias, Anita; Hop, Cornelis E C A; Rowbottom, Christopher; Evers, Raymond; Lai, Yurong; Kelly, Edward J; Prasad, Bhagwat; Unadkat, Jashvant D
肿瘤
肿瘤免疫
炎症/感染
细胞生物学
肝炎
发表日期：2018
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