日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting the hSSB1-INTS3 Interface: A Computational Screening Driven Approach to Identify Potential Modulators

针对 hSSB1-INTS3 界面:一种识别潜在调节剂的计算筛选驱动方法

Tabassum Khair Barbhuiya, Sam Beard, Esha T Shah, Steven Mason, Emma Bolderson, Ken O'Byrne, Luke W Guddat, Derek J Richard, Mark N Adams, Neha S Gandhi

Barrier-to-autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity

自身整合障碍因子 (Banf1) 通过调节 DNA 依赖性激酶 (DNA-PK) 活性来调节 DNA 双链断裂修复途径选择

Joshua T Burgess, Chee Man Cheong, Amila Suraweera, Thais Sobanski, Sam Beard, Keyur Dave, Maddison Rose, Didier Boucher, Laura V Croft, Mark N Adams, Kenneth O'Byrne, Derek J Richard, Emma Bolderson

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy

提高非小细胞肺癌中 CDCA3 水平可增强对铂类化疗的敏感性

Katrina Kildey, Neha S Gandhi, Katherine B Sahin, Esha T Shah, Eric Boittier, Pascal H G Duijf, Christopher Molloy, Joshua T Burgess, Sam Beard, Emma Bolderson, Amila Suraweera, Derek J Richard, Kenneth J O'Byrne, Mark N Adams

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

COMMD4 与组蛋白 H2A-H2B 二聚体一起发挥作用,及时修复 DNA 双链断裂

Amila Suraweera, Neha S Gandhi, Sam Beard, Joshua T Burgess, Laura V Croft, Emma Bolderson, Ali Naqi, Nicholas W Ashton, Mark N Adams, Kienan I Savage, Shu-Dong Zhang, Kenneth J O'Byrne, Derek J Richard

The Impact of Rare Human Variants on Barrier-To-Auto-Integration Factor 1 (Banf1) Structure and Function

罕见人类变异对屏障自整合因子 1 (Banf1) 结构和功能的影响

Maddison Rose, Bond Bai, Ming Tang, Chee Man Cheong, Sam Beard, Joshua T Burgess, Mark N Adams, Kenneth J O'Byrne, Derek J Richard, Neha S Gandhi, Emma Bolderson

Identification of Proteins Deregulated by Platinum-Based Chemotherapy as Novel Biomarkers and Therapeutic Targets in Non-Small Cell Lung Cancer

鉴定铂类化疗失调的蛋白质作为非小细胞肺癌的新型生物标志物和治疗靶点

Sarah-Louise Ryan, Keyur A Dave, Sam Beard, Martina Gyimesi, Matthew McTaggart, Katherine B Sahin, Christopher Molloy, Neha S Gandhi, Eric Boittier, Connor G O'Leary, Esha T Shah, Emma Bolderson, Anne-Marie Baird, Derek J Richard, Kenneth J O'Byrne, Mark N Adams

Defining COMMD4 as an anti-cancer therapeutic target and prognostic factor in non-small cell lung cancer

将 COMMD4 定义为非小细胞肺癌的抗癌治疗靶点和预后因素

Amila Suraweera, Alex Duff, Mark N Adams, Christian Jekimovs, Pascal H G Duijf, Cheng Liu, Matthew McTaggart, Sam Beard, Kenneth J O'Byrne, Derek J Richard

hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress

hSSB1 (NABP2/OBFC2B) 受氧化应激调控

Nicolas Paquet, Mark N Adams, Nicholas W Ashton, Christine Touma, Roland Gamsjaeger, Liza Cubeddu, Vincent Leong, Sam Beard, Emma Bolderson, Catherine H Botting, Kenneth J O'Byrne, Derek J Richard

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway

hSSB1 (NABP2/ OBFC2B) 是 hOGG1 介导的碱基切除修复途径修复 8-氧代鸟嘌呤所必需的

Nicolas Paquet, Mark N Adams, Vincent Leong, Nicholas W Ashton, Christine Touma, Roland Gamsjaeger, Liza Cubeddu, Sam Beard, Joshua T Burgess, Emma Bolderson, Ken J O'Byrne, Derek J Richard