日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes

白血病前期单细胞图谱揭示了突变特异性机制和基因程序,这些机制和程序可预测急性髓系白血病(AML)患者的预后。

Tomoya Isobe ,Iwo Kucinski ,Melania Barile ,Xiaonan Wang ,Rebecca Hannah ,Hugo P Bastos ,Shirom Chabra ,M S Vijayabaskar ,Katherine H M Sturgess ,Matthew J Williams ,George Giotopoulos ,Ludovica Marando ,Juan Li ,Justyna Rak ,Malgorzata Gozdecka ,Daniel Prins ,Mairi S Shepherd ,Sam Watcham ,Anthony R Green ,David G Kent ,George S Vassiliou ,Brian J P Huntly ,Nicola K Wilson ,Berthold Göttgens

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

两种醛类清除系统对于防止小鼠和人体内致命的甲醛积累至关重要。

Felix A Dingler ,Meng Wang ,Anfeng Mu ,Christopher L Millington ,Nina Oberbeck ,Sam Watcham ,Lucas B Pontel ,Ashley N Kamimae-Lanning ,Frederic Langevin ,Camille Nadler ,Rebecca L Cordell ,Paul S Monks ,Rui Yu ,Nicola K Wilson ,Asuka Hira ,Kenichi Yoshida ,Minako Mori ,Yusuke Okamoto ,Yusuke Okuno ,Hideki Muramatsu ,Yuichi Shiraishi ,Masayuki Kobayashi ,Toshinori Moriguchi ,Tomoo Osumi ,Motohiro Kato ,Satoru Miyano ,Etsuro Ito ,Seiji Kojima ,Hiromasa Yabe ,Miharu Yabe ,Keitaro Matsuo ,Seishi Ogawa ,Berthold Göttgens ,Michael R G Hodskinson ,Minoru Takata ,Ketan J Patel

The stem/progenitor landscape is reshaped in a mouse model of essential thrombocythemia and causes excess megakaryocyte production

在原发性血小板增多症小鼠模型中,干细胞/祖细胞格局发生重塑,导致巨核细胞过度生成。

Daniel Prins ,Hyun Jung Park ,Sam Watcham ,Juan Li ,Michele Vacca ,Hugo P Bastos ,Alexander Gerbaulet ,Antonio Vidal-Puig ,Berthold Göttgens ,Anthony R Green