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Influenza vaccination post-COVID-19 expands vaccine-specific effector CD4 T-cells and Tregs under positive influence of host trained innate immunity

新冠疫情后接种流感疫苗，在宿主已训练的先天免疫的积极影响下，可扩增疫苗特异性效应CD4 T细胞和调节性T细胞。

Bindhu, Hima; Rakshit, Srabanti; Adiga, Vasista; Ahmed, Asma; Kumar, Nirutha Chetan; Macrina, Maria; Tripathi, Himanshu; Vanni, Francesca; Montomoli, Emanuele; Samal, Sweety; Raj, Sneha; Vishwakarma, Preeti; Souza, George D; Sasidharan, Shruthi; Dias, Mary; Tree, Timothy; Vyakarnam, Annapurna

新冠

Next-gen novel nanocage-based multivalent vaccine candidate to tackle the rising menace of Mpox.

新一代新型纳米笼基多价疫苗候选物，用于应对日益严重的痘病毒威胁

期刊:NPJ Vaccines

影响因子:6.5

doi:10.1038/s41541-025-01174-1

Ahuja Rahul, Vishwakarma Preeti, Kumar Varun, Khatri Ritika, Chatterjee Ananya, Mishra Surbhi, Rizvi Zaigham Abbas, Singh Anup, Kaur Gurleen, Maithil Vikas, Tarane Kunal, Chauhan Akanksha, Singh Sarjeet, Yadav Pooja, Yadav Devendra, Sinha Sangita Kumari, Ali Syed Khalid, Chatterjee Abhisek, Priyadarsiny Priyanka, Awasthi Amit, Prasad Vidya Mangala, Ahmed Shubbir, Samal Sweety

微生物学

发表日期：2025

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CoviWall, a whole-virion-inactivated B.1.617.2 vaccine candidate, induces potent humoral and Th1 cell response in mice and protects against B.1.617.2 strain challenge in Syrian hamsters

CoviWall 是一种全病毒灭活的 B.1.617.2 候选疫苗，可在小鼠体内诱导强效的体液免疫和 Th1 细胞反应，并能保护叙利亚仓鼠免受 B.1.617.2 毒株的攻击。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2024.1447962

Dandotiya, Jyotsna; Adhikari, Neeta; Tripathy, Manas Ranjan; Jakhar, Kamini; Sonar, Sudipta; Pati, Dibya Ranjan; Kanchan, Vibhu; Prasad, Varsha S; Kumar, Jitendra; Senapati, Nitesh K; Bharmoria, Arti; Rani, Neeraj; Lakhanpal, Monika; Patil, C S; Singh, Nishan; Khan, Lovely; Jambu, Lavit; Jain, Naveen K; Ali, Syed Khalid; Priyadarsiny, Priyanka; Panda, Amulya K; Jain, Rajesh; Mani, Shailendra; Samal, Sweety; Awasthi, Amit; Rizvi, Zaigham Abbas

G4-binding drugs, chlorpromazine and prochlorperazine, repurposed against COVID-19 infection in hamsters.

G4 结合药物氯丙嗪和丙氯拉嗪被重新用于治疗仓鼠的 COVID-19 感染

期刊:Frontiers in Molecular Biosciences

影响因子:4

doi:10.3389/fmolb.2023.1133123

Roy Shuvra Shekhar, Sharma Shalu, Rizvi Zaigham Abbas, Sinha Dipanjali, Gupta Divya, Rophina Mercy, Sehgal Paras, Sadhu Srikanth, Tripathy Manas Ranjan, Samal Sweety, Maiti Souvik, Scaria Vinod, Sivasubbu Sridhar, Awasthi Amit, Harshan Krishnan H, Jain Sanjeev, Chowdhury Shantanu

炎症/感染

发表日期：2023

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Clinical and experimental evidence suggest omicron variant of SARS-CoV-2 is inherently less pathogenic than delta variant independent of previous immunity

临床和实验证据表明，无论既往免疫情况如何，SARS-CoV-2 的 omicron 变异株的致病性均低于 delta 变异株。

期刊:European Journal of Medical Research

影响因子:3.4

doi:10.1186/s40001-023-01373-3

Thiruvengadam, Ramachandran; Rizvi, Zaigham Abbas; Raghavan, Sreevatsan; Murugesan, Deepika Rathna; Gosain, Mudita; Dandotiya, Jyotsna; Ayushi; Samal, Sweety; Pandey, Anil K; Wadhwa, Nitya; Bhatnagar, Shinjini; Awasthi, Amit; Garg, Pramod Kumar

Designing and characterization of a SARS-CoV-2 immunogen with receptor binding motif grafted on a protein scaffold: An epitope-focused vaccine approach.

设计和表征一种在蛋白质支架上嫁接受体结合基序的 SARS-CoV-2 免疫原：一种以表位为中心的疫苗方法

期刊:International Journal of Biological Macromolecules

影响因子:8.5

doi:10.1016/j.ijbiomac.2022.04.148

Khatri Ritika, Parray Hilal Ahmad, Agrahari Ashish Kumar, Rizvi Zaigham Abbas, Kaul Rachel, Raj Sneha, Asthana Shailendra, Mani Shailendra, Samal Sweety, Awasthi Amit, Ahmed Shubbir

Biophysical and Biochemical Characterization of the Receptor Binding Domain of SARS-CoV-2 Variants

SARS-CoV-2 变体受体结合域的生物物理和生物化学表征

期刊:

影响因子:

doi:10.1007/s10930-022-10073-6

Khatri, Ritika; Parray, Hilal Ahmad; Siddiqui, Gazala; Chiranjivi, Adarsh Kumar; Raj, Sneha; Kaul, Rachel; Maithil, Vikas; Samal, Sweety; Ahmed, Shubbir

Inhalation monoclonal antibody therapy: a new way to treat and manage respiratory infections

吸入单克隆抗体疗法：治疗和控制呼吸道感染的新方法

期刊:Applied Microbiology and Biotechnology

影响因子:4.3

doi:10.1007/s00253-021-11488-4

Parray, Hilal Ahmad; Shukla, Shivangi; Perween, Reshma; Khatri, Ritika; Shrivastava, Tripti; Singh, Vanshika; Murugavelu, Praveenkumar; Ahmed, Shubbir; Samal, Sweety; Sharma, Chandresh; Sinha, Subrata; Luthra, Kalpana; Kumar, Rajesh

Correction: Tetramerizing tGCN4 domain facilitates production of Influenza A H1N1 M2e higher order soluble oligomers that show enhanced immunogenicity in vivo

更正：tGCN4结构域的四聚化促进了甲型H1N1流感病毒M2e高阶可溶性寡聚体的产生，这些寡聚体在体内显示出增强的免疫原性。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2021.100407

Samal, Sweety; Shrivastava, Tripti; Sonkusre, Praveen; Rizvi, Zaigham Abbas; Kumar, Rajesh; Ahmed, Shubbir; Vishwakarma, Preeti; Yadav, Naveen; Bansal, Manish; Chauhan, Kanchana; Pokhrel, Sebanta; Das, Supratik; Tambare, Padmakar; Awasthi, Amit

Pentameric M2e influenza vaccine candidate generates strong immunity with limited survival benefit

五聚体M2e流感疫苗候选物可产生强效免疫力，但生存获益有限。

Influenza vaccination post-COVID-19 expands vaccine-specific effector CD4 T-cells and Tregs under positive influence of host trained innate immunity

新冠疫情后接种流感疫苗，在宿主已训练的先天免疫的积极影响下，可扩增疫苗特异性效应CD4 T细胞和调节性T细胞。

Next-gen novel nanocage-based multivalent vaccine candidate to tackle the rising menace of Mpox.

新一代新型纳米笼基多价疫苗候选物，用于应对日益严重的痘病毒威胁

CoviWall, a whole-virion-inactivated B.1.617.2 vaccine candidate, induces potent humoral and Th1 cell response in mice and protects against B.1.617.2 strain challenge in Syrian hamsters

CoviWall 是一种全病毒灭活的 B.1.617.2 候选疫苗，可在小鼠体内诱导强效的体液免疫和 Th1 细胞反应，并能保护叙利亚仓鼠免受 B.1.617.2 毒株的攻击。

G4-binding drugs, chlorpromazine and prochlorperazine, repurposed against COVID-19 infection in hamsters.

G4 结合药物氯丙嗪和丙氯拉嗪被重新用于治疗仓鼠的 COVID-19 感染

Clinical and experimental evidence suggest omicron variant of SARS-CoV-2 is inherently less pathogenic than delta variant independent of previous immunity

临床和实验证据表明，无论既往免疫情况如何，SARS-CoV-2 的 omicron 变异株的致病性均低于 delta 变异株。

Designing and characterization of a SARS-CoV-2 immunogen with receptor binding motif grafted on a protein scaffold: An epitope-focused vaccine approach.

设计和表征一种在蛋白质支架上嫁接受体结合基序的 SARS-CoV-2 免疫原：一种以表位为中心的疫苗方法

Biophysical and Biochemical Characterization of the Receptor Binding Domain of SARS-CoV-2 Variants

SARS-CoV-2 变体受体结合域的生物物理和生物化学表征

Inhalation monoclonal antibody therapy: a new way to treat and manage respiratory infections

吸入单克隆抗体疗法：治疗和控制呼吸道感染的新方法

Correction: Tetramerizing tGCN4 domain facilitates production of Influenza A H1N1 M2e higher order soluble oligomers that show enhanced immunogenicity in vivo

更正：tGCN4结构域的四聚化促进了甲型H1N1流感病毒M2e高阶可溶性寡聚体的产生，这些寡聚体在体内显示出增强的免疫原性。