日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pacritinib abrogates the lupus phenotype in ABIN1[D485N] mice

帕克里替尼可消除 ABIN1[D485N] 小鼠的狼疮表型

Tsvetana Petrova, Clara Figueras-Vadillo, Sambit K Nanda, Cheryl Scudamore, Philip Cohen

HOIL-1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation

HOIL-1 泛素连接酶活性靶向无支链葡萄糖,是防止多聚葡萄糖积累所必需的

Ian R Kelsall, Elisha H McCrory, Yingqi Xu, Cheryl L Scudamore, Sambit K Nanda, Paula Mancebo-Gamella, Nicola T Wood, Axel Knebel, Stephen J Matthews, Philip Cohen

IKKβ is required for the formation of the NLRP3 inflammasome

IKKβ 是 NLRP3 炎症小体形成所必需的

Sambit K Nanda, Alan R Prescott, Clara Figueras-Vadillo, Philip Cohen

HOIL-1-catalysed, ester-linked ubiquitylation restricts IL-18 signaling in cytotoxic T cells but promotes TLR signalling in macrophages

HOIL-1 催化的酯键泛素化限制了细胞毒性 T 细胞中的 IL-18 信号传导,但促进了巨噬细胞中的 TLR 信号传导

Tsvetana Petrova, Jiazhen Zhang, Sambit K Nanda, Clara Figueras-Vadillo, Philip Cohen

Prevention and partial reversion of the lupus phenotype in ABIN1[D485N] mice by an IRAK4 inhibitor

IRAK4 抑制剂可预防和部分逆转 ABIN1[D485N] 小鼠的狼疮表型

Tsvetana Petrova, Sambit K Nanda, Cheryl Scudamore, Stephen W Wright, Vikram R Rao, Philip Cohen

ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism

ABIN2 功能是通过 Tpl2 独立的机制抑制 DSS 诱发的结肠炎所必需的

Sambit K Nanda, Tsunehisa Nagamori, Mark Windheim, Sylvia Amu, Gabriella Aviello, Janet Patterson-Kane, J Simon C Arthur, Steven C Ley, Padraic Fallon, Philip Cohen

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity

多泛素与 ABIN1 结合是预防自身免疫的必要条件

Sambit K Nanda, Ram K C Venigalla, Alban Ordureau, Janet C Patterson-Kane, David W Powell, Rachel Toth, J Simon C Arthur, Philip Cohen