Samelson Lawrence E相关文献与解析，生知库

Weak SLP-76-PLC-γ1 interaction in the LAT-nucleated multi-protein complex fine-tunes TCR signal strength to optimize T cell responsiveness

LAT成核多蛋白复合物中SLP-76-PLC-γ1的弱相互作用可微调TCR信号强度，从而优化T细胞反应性。

doi:10.1101/2025.09.11.675682

Yamane, Hidehiro; Wada, Junya; Stassenko, Elizabeth N; Convertino, Natalie D; Lee, Mariah E; Vacchio, Melanie S; Li, Wenmei; Rathnayake, Udumbara M; Balagopalan, Lakshmi; Chari, Raj; Hagenau, Herbert; Awasthi, Parirokh; McGavern, Dorian B; Bosselut, Remy; Samelson, Lawrence E

Microclusters as T Cell Signaling Hubs: Structure, Kinetics, and Regulation

微簇作为T细胞信号传导枢纽：结构、动力学和调控

期刊:Frontiers in Cell and Developmental Biology

影响因子:4.3

doi:10.3389/fcell.2020.608530

Balagopalan, Lakshmi; Raychaudhuri, Kumarkrishna; Samelson, Lawrence E

Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7

Pak1激酶通过调节L-选择素和CCR7的表达促进活化T细胞的迁移

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2019.00370

Dios-Esponera, Ana; Melis, Nicolas; Subramanian, Bhagawat C; Weigert, Roberto; Samelson, Lawrence E

Unexpected Cartilage Phenotype in CD4-Cre-Conditional SOS-Deficient Mice

CD4-Cre条件性SOS缺陷小鼠的意外软骨表型

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2017.00343

Guittard, Geoffrey; Gallardo, Devorah L; Li, Wenmei; Melis, Nicolas; Lui, Julian C; Kortum, Robert L; Shakarishvili, Nicholas G; Huh, Sunmee; Baron, Jeffrey; Weigert, Roberto; Kramer, Joshua A; Samelson, Lawrence E; Sommers, Connie L

Super-resolution Analysis of TCR-Dependent Signaling: Single-Molecule Localization Microscopy

TCR依赖性信号传导的超分辨率分析：单分子定位显微镜

期刊:Methods in Molecular Biology

影响因子:

doi:10.1007/978-1-4939-6881-7_13

Barr, Valarie A; Yi, Jason; Samelson, Lawrence E

信号转导

发表日期：2017

文献求助收藏

Hierarchical nanostructure and synergy of multimolecular signalling complexes

分级纳米结构和多分子信号复合物的协同作用

期刊:Nature Communications

影响因子:15.7

doi:10.1038/ncomms12161

Sherman, Eilon; Barr, Valarie A; Merrill, Robert K; Regan, Carole K; Sommers, Connie L; Samelson, Lawrence E

信号转导

发表日期：2016

文献求助收藏

Microvilli set the stage for T-cell activation

微绒毛为T细胞活化创造了条件。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1613832113

Yi, Jason C; Samelson, Lawrence E

The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclusters

T细胞活化连接蛋白（LAT）信号枢纽：从信号复合物到微簇

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.R115.665869

Balagopalan, Lakshmi; Kortum, Robert L; Coussens, Nathan P; Barr, Valarie A; Samelson, Lawrence E

Cytoskeletal forces during signaling activation in Jurkat T-cells

Jurkat T细胞信号激活过程中细胞骨架的力

期刊:Molecular Biology of the Cell

影响因子:2.7

doi:10.1091/mbc.E14-03-0830

Hui, King Lam; Balagopalan, Lakshmi; Samelson, Lawrence E; Upadhyaya, Arpita

Purification and characterization of full-length monomeric TEC family kinase, ITK.

全长单体TEC家族激酶ITK的纯化和表征

Weak SLP-76-PLC-γ1 interaction in the LAT-nucleated multi-protein complex fine-tunes TCR signal strength to optimize T cell responsiveness

LAT成核多蛋白复合物中SLP-76-PLC-γ1的弱相互作用可微调TCR信号强度，从而优化T细胞反应性。

Microclusters as T Cell Signaling Hubs: Structure, Kinetics, and Regulation

微簇作为T细胞信号传导枢纽：结构、动力学和调控

Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7

Pak1激酶通过调节L-选择素和CCR7的表达促进活化T细胞的迁移

Unexpected Cartilage Phenotype in CD4-Cre-Conditional SOS-Deficient Mice

CD4-Cre条件性SOS缺陷小鼠的意外软骨表型

Super-resolution Analysis of TCR-Dependent Signaling: Single-Molecule Localization Microscopy

TCR依赖性信号传导的超分辨率分析：单分子定位显微镜

Hierarchical nanostructure and synergy of multimolecular signalling complexes

分级纳米结构和多分子信号复合物的协同作用

Microvilli set the stage for T-cell activation

微绒毛为T细胞活化创造了条件。

The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclusters

T细胞活化连接蛋白（LAT）信号枢纽：从信号复合物到微簇

Cytoskeletal forces during signaling activation in Jurkat T-cells

Jurkat T细胞信号激活过程中细胞骨架的力