日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Efficacy and safety of the HIV-1 maturation inhibitor GSK3640254 plus two NRTIs in adults naive to antiretroviral therapy (DOMINO): 24-week results from a randomised phase 2b study

HIV-1成熟抑制剂GSK3640254联合两种核苷类逆转录酶抑制剂治疗未接受过抗逆转录病毒治疗的成年患者的疗效和安全性（DOMINO）：一项随机2b期研究的24周结果

期刊:EClinicalMedicine
影响因子:10
doi:10.1016/j.eclinm.2025.103567
Joshi, Samit R; Cordova, Ezequiel; Mitha, Essack; Castagna, Antonella; Ramgopal, Moti; Llibre, Josep M; Potthoff, Anja; Chernova, Oksana E; Nuñez, Sebastian A; Man, Choy; Jeffrey, Jerry L; Fishman, Cindy; Oyee, James; Joshi, Aditya; Zhang, Ying; Bainbridge, Veronica; Wynne, Brian; Lataillade, Max
HIV
GSK3
微生物学
发表日期：2025
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Efficacy and safety of the HIV-1 maturation inhibitor GSK3640254 plus dolutegravir as a two-drug regimen in adults naive to antiretroviral therapy (DYNAMIC): 24-week results from a randomised phase 2b study

在未接受过抗逆转录病毒治疗的成人患者中，HIV-1成熟抑制剂GSK3640254联合多替拉韦作为双药方案的疗效和安全性（DYNAMIC）：一项随机2b期研究的24周结果

期刊:EClinicalMedicine
影响因子:10
doi:10.1016/j.eclinm.2025.103566
Joshi, Samit R; Masiá, Mar; Mitha, Essack; Castagna, Antonella; Cordova, Ezequiel; Ramgopal, Moti; Gaudion, Alison; Karthika, Supriya; Oyee, James; Bainbridge, Veronica; Wynne, Brian; Lataillade, Max
HIV
GSK3
微生物学
发表日期：2025
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Phase IIa Proof-of-Concept Evaluation of the Antiviral Efficacy, Safety, Tolerability, and Pharmacokinetics of the Next-Generation Maturation Inhibitor GSK3640254

下一代成熟抑制剂 GSK3640254 的抗病毒疗效、安全性、耐受性和药代动力学 IIa 期概念验证评估

期刊:Clinical Infectious Diseases
影响因子:7.3
doi:10.1093/cid/ciab1065
Spinner, Christoph D; Felizarta, Franco; Rizzardini, Giuliano; Philibert, Patrick; Mitha, Essack; Domingo, Pere; Stephan, Christoph J; DeGrosky, Michelle; Bainbridge, Veronica; Zhan, Joyce; Dumitrescu, Teodora Pene; Jeffrey, Jerry L; Xu, Jianfeng; Halliday, Fiona; Gan, Jianjun; Johnson, Mark; Gartland, Martin; Joshi, Samit R; Lataillade, Max
微生物学
GSK3
发表日期：2022
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Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults

健康青年和老年人流感疫苗反应的代谢组学和转录组学特征

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.13682
Chou, Chih-Hung; Mohanty, Subhasis; Kang, Heather A; Kong, Lingjia; Avila-Pacheco, Julian; Joshi, Samit R; Ueda, Ikuyo; Devine, Lesley; Raddassi, Khadir; Pierce, Kerry; Jeanfavre, Sarah; Bullock, Kevin; Meng, Hailong; Clish, Clary; Santori, Fabio R; Shaw, Albert C; Xavier, Ramnik J
微生物学
流感
代谢
发表日期：2022
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Lack of pharmacokinetic interaction between the HIV-1 maturation inhibitor GSK3640254 and combination oral contraceptives in healthy women

健康女性中HIV-1成熟抑制剂GSK3640254与复方口服避孕药之间缺乏药代动力学相互作用

期刊:British Journal of Clinical Pharmacology
影响因子:3
doi:10.1111/bcp.15051
Pene Dumitrescu, Teodora; Greene, Thomas J; Joshi, Samit R; Xu, Jianfeng; Johnson, Mark; Halliday, Fiona; Butcher, Laurie; Zimmerman, Eric; Webster, Lindsey; Pham, Theresa T; Lataillade, Max; Min, Sherene
HIV
GSK3
微生物学
发表日期：2022
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A Phase I Evaluation of the Pharmacokinetics and Tolerability of the HIV-1 Maturation Inhibitor GSK3640254 and Tenofovir Alafenamide/Emtricitabine in Healthy Participants

在健康受试者中评估 HIV-1 成熟抑制剂 GSK3640254 和替诺福韦艾拉酚胺/恩曲他滨的药代动力学和耐受性的 I 期研究

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.02173-20
Pene Dumitrescu, Teodora; Joshi, Samit R; Xu, Jianfeng; Zhan, Joyce; Johnson, Mark; Butcher, Laurie; Zimmerman, Eric; Webster, Lindsey; Davidson, Antonia M; Lataillade, Max; Min, Sherene
HIV
GSK3
微生物学
发表日期：2021
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Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected adults: Week 24 primary analysis from a randomized Phase IIb trial

在未经治疗的 HIV-1 感染成人中，成熟抑制剂 GSK3532795（曾用名 BMS-955176）联合替诺福韦/恩曲他滨每日一次的安全性、有效性和剂量反应：一项随机 IIb 期试验的第 24 周主要分析

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0205368
Morales-Ramirez, Javier; Bogner, Johannes R; Molina, Jean-Michel; Lombaard, Johan; Dicker, Ira B; Stock, David A; DeGrosky, Michelle; Gartland, Margaret; Pene Dumitrescu, Teodora; Min, Sherene; Llamoso, Cyril; Joshi, Samit R; Lataillade, Max
HIV
炎症/感染
多发性硬化症
微生物学
GSK3
发表日期：2018
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Multiple network-constrained regressions expand insights into influenza vaccination responses

多重网络约束回归分析加深了对流感疫苗接种反应的理解

期刊:
影响因子:
doi:10.1093/bioinformatics/btx260
Avey, Stefan; Mohanty, Subhasis; Wilson, Jean; Zapata, Heidi; Joshi, Samit R; Siconolfi, Barbara; Tsang, Sui; Shaw, Albert C; Kleinstein, Steven H
微生物学
流感
发表日期：2017
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Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults

老年人接种流感疫苗后白细胞介素 10 调节单核细胞中促炎细胞因子的产生延长

期刊:Journal of Infectious Diseases
影响因子:5
doi:10.1093/infdis/jiu573
Subhasis Mohanty, Samit R Joshi, Ikuyo Ueda, Jean Wilson, Tamara P Blevins, Barbara Siconolfi, Hailong Meng, Lesley Devine, Khadir Raddassi, Sui Tsang, Robert B Belshe, David A Hafler, Susan M Kaech, Steven H Kleinstein, Mark Trentalange, Heather G Allore, Albert C Shaw
免疫
流感
单核细胞
发表日期：2015
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Safety profile of HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 analysis

HIV-1 附着抑制剂前药 BMS-663068 在既往接受过抗逆转录病毒治疗的受试者中的安全性概况：第 24 周分析

期刊:Journal of the International Aids Society
影响因子:4.9
doi:10.7448/IAS.17.4.19530
Lalezari, Jacob; Latiff, Gulam H; Brinson, Cynthia; Echevarria, Juan; Treviño-Pérez, Sandra; Bogner, Johannes R; Stock, David; Joshi, Samit R; Hanna, George J; Lataillade, Max
HIV
多发性硬化症
微生物学
发表日期：2014
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