日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic targeting of the NOTCH1 and neddylation pathways in T cell acute lymphoblastic leukemia.

T细胞急性淋巴细胞白血病中NOTCH1和neddylation通路的治疗靶向治疗

Bertulfo Kalay, Perez-Duran Pablo, Miller Hannah, Ma Cindy, Ambesi-Impiombato Alberto, Samon Jeremy, Mackey Adam, Lin Wen-Hsuan Wendy, Ferrando Adolfo A, Palomero Teresa

Runx transcription factors repress human and murine c-Myc expression in a DNA-binding and C-terminally dependent manner

Runx转录因子以DNA结合和C端依赖的方式抑制人和小鼠c-Myc的表达。

Jacobs, Paejonette T; Cao, Li; Samon, Jeremy B; Kane, Christyne A; Hedblom, Emmett E; Bowcock, Anne; Telfer, Janice C

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

T细胞急性淋巴细胞白血病中多梳抑制复合物2的基因失活

Ntziachristos, Panagiotis; Tsirigos, Aristotelis; Van Vlierberghe, Pieter; Nedjic, Jelena; Trimarchi, Thomas; Flaherty, Maria Sol; Ferres-Marco, Dolors; da Ros, Vanina; Tang, Zuojian; Siegle, Jasmin; Asp, Patrik; Hadler, Michael; Rigo, Isaura; De Keersmaecker, Kim; Patel, Jay; Huynh, Tien; Utro, Filippo; Poglio, Sandrine; Samon, Jeremy B; Paietta, Elisabeth; Racevskis, Janis; Rowe, Jacob M; Rabadan, Raul; Levine, Ross L; Brown, Stuart; Pflumio, Francoise; Dominguez, Maria; Ferrando, Adolfo; Aifantis, Iannis

Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia

γ-分泌酶抑制剂PF-03084014联合糖皮质激素治疗T细胞急性淋巴细胞白血病的临床前分析

Samon, Jeremy B; Castillo-Martin, Mireia; Hadler, Michael; Ambesi-Impiobato, Alberto; Paietta, Elisabeth; Racevskis, Janis; Wiernik, Peter H; Rowe, Jacob M; Jakubczak, John; Randolph, Sophia; Cordon-Cardo, Carlos; Ferrando, Adolfo A

Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells

Notch1和TGFβ1协同调节Foxp3表达和外周调节性T细胞的维持。

Samon, Jeremy B; Champhekar, Ameya; Minter, Lisa M; Telfer, Janice C; Miele, Lucio; Fauq, Abdul; Das, Pritam; Golde, Todd E; Osborne, Barbara A