日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits

同步CRISPR筛选和空间转录组学揭示细胞内、细胞间和功能性转录回路

Loϊc Binan ,Aiping Jiang ,Serwah A Danquah ,Vera Valakh ,Brooke Simonton ,Jon Bezney ,Robert T Manguso ,Kathleen B Yates ,Ralda Nehme ,Brian Cleary ,Samouil L Farhi

Characterizing protein sequence determinants of nuclear condensates by high-throughput pooled imaging with CondenSeq

利用 CondenSeq 技术进行高通量混合成像,表征核凝聚体的蛋白质序列决定因素

Kalli Kappel,Daniel Strebinger,KeHuan K Edmonds,Samuel Chau-Duy-Tam Vo,Christopher M Vockley,Tridib Biswas,Samouil L Farhi,Rhiannon Macrae,Feng Zhang,Aviv Regev

Coordinated immune networks in leukemia bone marrow microenvironments distinguish response to cellular therapy

白血病骨髓微环境中协调的免疫网络决定了对细胞疗法的反应

Maurer, Katie; Park, Cameron Y; Mani, Shouvik; Borji, Mehdi; Raths, Florian; Gouin, Kenneth H 3rd; Penter, Livius; Jin, Yinuo; Zhang, Jia Yi; Shin, Crystal; Brenner, James R; Southard, Jackson; Krishna, Sachi; Lu, Wesley; Lyu, Haoxiang; Abbondanza, Domenic; Mangum, Chanell; Olsen, Lars Rønn; Lawson, Michael J; Fabani, Martin; Neuberg, Donna S; Bachireddy, Pavan; Glezer, Eli N; Farhi, Samouil L; Li, Shuqiang; Livak, Kenneth J; Ritz, Jerome; Soiffer, Robert J; Wu, Catherine J; Azizi, Elham

Single-cell and spatiotemporal profile of ovulation in the mouse ovary.

小鼠卵巢排卵的单细胞和时空特征

Huang Ruixu, Kratka Caroline E, Pea Jeffrey, McCann Cai, Nelson Jack, Bryan John P, Zhou Luhan T, Russo Daniela D, Zaniker-Gomez Emily J, Gandhi Achla H, Shalek Alex K, Cleary Brian, Farhi Samouil L, Duncan Francesca E, Goods Brittany A

Accurate trajectory inference in time-series spatial transcriptomics with structurally-constrained optimal transport

利用结构约束最优传输进行时间序列空间转录组学中的精确轨迹推断

Bryan, John P; Farhi, Samouil L; Cleary, Brian

CellPHIE: Integrating Pathway Discovery With Pooled Profiling of Perturbations Uncovers Pathways of Huntington's Disease, Including Genetic Modifiers of Neuronal Development and Morphology.

CellPHIE:将通路发现与扰动汇总分析相结合,揭示了亨廷顿病的通路,包括神经元发育和形态的遗传修饰因子

Kang Byunguk, Murphy Michael, Ng Christopher W, Leventhal Matthew Joseph, Huynh Nhan, Im Egun, Danquah Serwah, Housman David E, Nehme Ralda, Farhi Samouil L, Fraenkel Ernest

Robust self-supervised denoising of voltage imaging data using CellMincer

使用 CellMincer 对电压图像数据进行稳健的自监督去噪

Brice Wang, Tianle Ma, Theresa Chen, Trinh Nguyen, Ethan Crouse, Stephen J Fleming, Alison S Walker, Vera Valakh, Ralda Nehme, Evan W Miller, Samouil L Farhi, Mehrtash Babadi

Coordinated Immune Cell Networks in the Bone Marrow Microenvironment Define the Graft versus Leukemia Response with Adoptive Cellular Therapy

骨髓微环境中协调的免疫细胞网络决定了过继细胞疗法中的移植物抗白血病反应

Maurer, Katie; Park, Cameron Y; Mani, Shouvik; Borji, Mehdi; Penter, Livius; Jin, Yinuo; Zhang, Jia Yi; Shin, Crystal; Brenner, James R; Southard, Jackson; Krishna, Sachi; Lu, Wesley; Lyu, Haoxiang; Abbondanza, Domenic; Mangum, Chanell; Olsen, Lars Rønn; Neuberg, Donna S; Bachireddy, Pavan; Farhi, Samouil L; Li, Shuqiang; Livak, Kenneth J; Ritz, Jerome; Soiffer, Robert J; Wu, Catherine J; Azizi, Elham

Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons

与精神分裂症相关的星形胶质细胞粘附基因与神经元中的突触程序相关

Olli Pietiläinen, Aditi Trehan, Daniel Meyer, Jana Mitchell, Matthew Tegtmeyer, Vera Valakh, Hilena Gebre, Theresa Chen, Emilia Vartiainen, Samouil L Farhi, Kevin Eggan, Steven A McCarroll, Ralda Nehme

Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells

利用 NGN2 表达在人类多能干细胞中强力诱导功能性星形胶质细胞

Martin H Berryer, Matthew Tegtmeyer, Loïc Binan, Vera Valakh, Anna Nathanson, Darina Trendafilova, Ethan Crouse, Jenny A Klein, Daniel Meyer, Olli Pietiläinen, Francesca Rapino, Samouil L Farhi, Lee L Rubin, Steven A McCarroll, Ralda Nehme, Lindy E Barrett