Chemical synthesis of 7-oxygenated 12α-hydroxy steroid derivatives to enable the biochemical characterization of cytochrome P450 8B1, the oxysterol 12α-hydroxylase enzyme implicated in cardiovascular health and obesity
7-氧合12α-羟基类固醇衍生物的化学合成,用于对细胞色素 P450 8B1(与心血管健康和肥胖有关的氧固醇 12α-羟化酶)进行生化表征
期刊:Steroids
影响因子:2.1
doi:10.1016/j.steroids.2018.10.010
Samuel D Offei, Hadi D Arman, Mirza Oais Baig, Lazaro S Chavez, Carlos A Paladini, Francis K Yoshimoto