Mutations in the RAS/MAPK Pathway Drive Replication Repair-Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition
RAS/MAPK 通路突变会引发复制修复缺陷型高突变肿瘤，并使其对 MEK 抑制产生敏感性
期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-20-1050
Brittany B Campbell #, Melissa A Galati #, Simone C Stone, Alexandra N Riemenschneider, Melissa Edwards, Sumedha Sudhaman, Robert Siddaway, Martin Komosa, Nuno M Nunes, Liana Nobre, A Sorana Morrissy, Matthew Zatzman, Michal Zapotocky, Lazar Joksimovic, Sangeetha N Kalimuthu, David Samuel, Gary Maso
