日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of Wee1 as a target in combination with avapritinib for gastrointestinal stromal tumor treatment

确定 Wee1 作为与 avapritinib 联合治疗胃肠道间质瘤的靶点

Shuai Ye, Dinara Sharipova, Marya Kozinova, Lilli Klug, Jimson D'Souza, Martin G Belinsky, Katherine J Johnson, Margret B Einarson, Karthik Devarajan, Yan Zhou, Samuel Litwin, Michael C Heinrich, Ronald DeMatteo, Margaret von Mehren, James S Duncan, Lori Rink

Targeted blockade of HSP90 impairs DNA-damage response proteins and increases the sensitivity of ovarian carcinoma cells to PARP inhibition

靶向阻断 HSP90 可损害 DNA 损伤反应蛋白并增加卵巢癌细胞对 PARP 抑制的敏感性

Rashid Gabbasov, I Daniel Benrubi, Shane W O'Brien, John J Krais, Neil Johnson, Samuel Litwin, Denise C Connolly

NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice

NEDD9 促进小鼠的致癌信号、干细胞/间充质基因特征和卵巢癌的侵袭性生长

Rashid Gabbasov, Fang Xiao, Caitlin G Howe, Laura E Bickel, Shane W O'Brien, Daniel Benrubi, Thuy-Vy Do, Yan Zhou, Emmanuelle Nicolas, Kathy Q Cai, Samuel Litwin, Sachiko Seo, Erica A Golemis, Denise C Connolly

Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth

靶向阻断JAK/STAT3信号可抑制卵巢癌生长

Galina Gritsina, Fang Xiao, Shane W O'Brien, Rashid Gabbasov, Marisa A Maglaty, Ren-Huan Xu, Roshan J Thapa, Yan Zhou, Emmanuelle Nicolas, Samuel Litwin, Siddharth Balachandran, Luis J Sigal, Dennis Huszar, Denise C Connolly

Combining anti-ERBB3 antibodies specific for domain I and domain III enhances the anti-tumor activity over the individual monoclonal antibodies

将针对结构域 I 和结构域 III 的抗 ERBB3 抗体组合起来,可以增强单个单克隆抗体的抗肿瘤活性

Jimson W D'Souza, Smitha Reddy, Lisa E Goldsmith, Irina Shchaveleva, James D Marks, Samuel Litwin, Matthew K Robinson

Network analysis identifies an HSP90-central hub susceptible in ovarian cancer

网络分析确定卵巢癌中 HSP90 中心枢纽易感因素

Hanqing Liu, Fang Xiao, Ilya G Serebriiskii, Shane W O'Brien, Marisa A Maglaty, Igor Astsaturov, Samuel Litwin, Lainie P Martin, David A Proia, Erica A Golemis, Denise C Connolly

Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein

通过表达一种新型合成蛋白来改变基于HIV-1载体的整合位点偏好性

Robert M Silvers,Johanna A Smith, Michael Schowalter, Samuel Litwin, Zhihui Liang, Kyla Geary, René Daniel

Improved therapeutic results by pretargeted radioimmunotherapy of non-Hodgkin's lymphoma with a new recombinant, trivalent, anti-CD20, bispecific antibody

使用新型重组三价抗 CD20 双特异性抗体对非霍奇金淋巴瘤进行预定位放射免疫治疗,改善治疗效果

Robert M Sharkey, Habibe Karacay, Samuel Litwin, Edmund A Rossi, William J McBride, Chien-Hsing Chang, David M Goldenberg

One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis

癌症的一次性效应:家族性腺瘤性息肉病中形态正常的结肠隐窝蛋白质组发生改变

Anthony T Yeung, Bhavinkumar B Patel, Xin-Ming Li, Steven H Seeholzer, Renata A Coudry, Harry S Cooper, Alfonso Bellacosa, Bruce M Boman, Tao Zhang, Samuel Litwin, Eric A Ross, Peggy Conrad, James A Crowell, Levy Kopelovich, Alfred Knudson

Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver

感染肝炎病毒的肝脏中共价闭合环状 DNA 拷贝数的单细胞分析

Yong-Yuan Zhang, Bai-Hua Zhang, Daniel Theele, Samuel Litwin, Eugene Toll, Jesse Summers