Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice
阻止BMP4前结构域磷酸化的突变会损害同源二聚体的蛋白水解成熟,从而导致小鼠死亡。
期刊:
影响因子:
doi:10.1101/2024.10.08.617306
Kim, Hyung-Seok; Sanchez, Mary L; Silva, Joshua; Schubert, Heidi L; Dennis, Rebecca; Hill, Christopher P; Christian, Jan L