P-Glycoprotein (ABCB1/MDR1) and BCRP (ABCG2) Limit Brain Accumulation and Cytochrome P450-3A (CYP3A) Restricts Oral Exposure of the RET Inhibitor Selpercatinib (RETEVMO)
P-糖蛋白 (ABCB1/MDR1) 和 BCRP (ABCG2) 限制脑内蓄积，细胞色素 P450-3A (CYP3A) 限制 RET 抑制剂 Selpercatinib (RETEVMO) 的口服暴露
期刊:Pharmaceuticals
影响因子:
doi:10.3390/ph14111087
Yaogeng Wang, Rolf W Sparidans, Sander Potters, Rahime Şentürk, Maria C Lebre, Jos H Beijnen, Alfred H Schinkel
