Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models
氧感应脯氨酰羟化酶的治疗靶向消除了 ATF4 依赖性神经元死亡，并改善了几种啮齿动物模型中脑出血后的预后
期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.aac6008
Saravanan S Karuppagounder, Ishraq Alim, Soah J Khim, Megan W Bourassa, Sama F Sleiman, Roseleen John, Cyrille C Thinnes, Tzu-Lan Yeh, Marina Demetriades, Sandra Neitemeier, Dana Cruz, Irina Gazaryan, David W Killilea, Lewis Morgenstern, Guohua Xi, Richard F Keep, Timothy Schallert, Ryan V Tappero,
