The deubiquitinase USP9X and E3 ligase WWP1 orchestrate IGF2BP2 ubiquitination homeostasis to drive TNBC progression and cisplatin sensitivity.
去泛素化酶 USP9X 和 E3 连接酶 WWP1 协调 IGF2BP2 泛素化稳态，从而驱动 TNBC 进展和顺铂敏感性。
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-08038-5
Xia Tian, Zhao Jianyi, Zhang Zhengyu, Lu Weilin, Wang Yuxin, Dong Xinrui, Sang Mingyi, Ju Linjie, Zhang Xu, Wei Jifu, Ding Qiang
