日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic determinants of micronucleus formation in vivo

体内微核形成的遗传决定因素

D J Adams, B Barlas #, R E McIntyre #, I Salguero, L van der Weyden, A Barros, J R Vicente, N Karimpour, A Haider, M Ranzani, G Turner, N A Thompson, V Harle, R Olvera-León, C D Robles-Espinoza, A O Speak, N Geisler, W J Weninger, S H Geyer, J Hewinson, N A Karp; Sanger Mouse Genetics Project; B Fu,

High-throughput genotyping of high-homology mutant mouse strains by next-generation sequencing

通过下一代测序对高同源性突变小鼠品系进行高通量基因分型

Diane Gleeson, Debarati Sethi, Radka Platte, Jonathan Burvill, Daniel Barrett, Shaheen Akhtar, Michaela Bruntraeger, Joanna Bottomley, Sanger Mouse Genetics Project, James Bussell, Edward Ryder

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

针对 NAT10 可延长人类加速衰老综合征小鼠模型的健康寿命

Gabriel Balmus, Delphine Larrieu, Ana C Barros, Casey Collins, Monica Abrudan, Mukerrem Demir, Nicola J Geisler, Christopher J Lelliott, Jacqueline K White, Natasha A Karp, James Atkinson, Andrea Kirton, Matt Jacobsen, Dean Clift, Raphael Rodriguez; Sanger Mouse Genetics Project; David J Adams, Step

The AMP-activated protein kinase beta 1 subunit modulates erythrocyte integrity

AMP 活化蛋白激酶 β1 亚基调节红细胞完整性

Emma L Cambridge, Zoe McIntyre, Simon Clare, Mark J Arends, David Goulding, Christopher Isherwood, Susana S Caetano, Carmen Ballesteros Reviriego, Agnieszka Swiatkowska, Leanne Kane, Katherine Harcourt; Sanger Mouse Genetics Project; David J Adams, Jacqueline K White, Anneliese O Speak

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy

WD40-重复 47 是一种微管相关蛋白,对大脑发育和自噬至关重要

Meghna Kannan, Efil Bayam, Christel Wagner, Bruno Rinaldi, Perrine F Kretz, Peggy Tilly, Marna Roos, Lara McGillewie, Séverine Bär, Shilpi Minocha, Claire Chevalier, Chrystelle Po; Sanger Mouse Genetics Project; Jamel Chelly, Jean-Louis Mandel, Renato Borgatti, Amélie Piton, Craig Kinnear, Ben Loos,

Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol

Mrap2 的缺失与 Sim1 的缺乏和循环胆固醇的增加有关

T V Novoselova, R Larder, D Rimmington, C Lelliott, E H Wynn, R J Gorrigan, P H Tate, L Guasti; Sanger Mouse Genetics Project; S O'Rahilly, A J L Clark, D W Logan, A P Coll, L F Chan

High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice

高脂喂养可迅速诱发 C57BL/6N 小鼠肥胖和脂质紊乱

Christine Podrini, Emma L Cambridge, Christopher J Lelliott, Damian M Carragher, Jeanne Estabel, Anna-Karin Gerdin, Natasha A Karp, Cheryl L Scudamore; Sanger Mouse Genetics Project; Ramiro Ramirez-Solis, Jacqueline K White

The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation

组蛋白H2A-去泛素化酶Mysm1在造血和淋巴细胞分化中的关键作用

Anastasia Nijnik, Simon Clare, Christine Hale, Claire Raisen, Rebecca E McIntyre, Kosuke Yusa, Aaron R Everitt, Lynda Mottram, Christine Podrini, Mark Lucas, Jeanne Estabel, David Goulding; Sanger Institute Microarray Facility; Sanger Mouse Genetics Project; Niels Adams, Ramiro Ramirez-Solis, Jacqui

The role of sphingosine-1-phosphate transporter Spns2 in immune system function

鞘氨醇-1-磷酸转运体 Spns2 在免疫系统功能中的作用

Anastasia Nijnik, Simon Clare, Christine Hale, Jing Chen, Claire Raisen, Lynda Mottram, Mark Lucas, Jeanne Estabel, Edward Ryder, Hibret Adissu; Sanger Mouse Genetics Project; Niels C Adams, Ramiro Ramirez-Solis, Jacqueline K White, Karen P Steel, Gordon Dougan, Robert E W Hancock

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome

破坏小鼠 Cenpj(中心粒生物合成的调节剂)可模拟塞克尔综合征

Rebecca E McIntyre, Pavithra Lakshminarasimhan Chavali, Ozama Ismail, Damian M Carragher, Gabriela Sanchez-Andrade, Josep V Forment, Beiyuan Fu, Martin Del Castillo Velasco-Herrera, Andrew Edwards, Louise van der Weyden, Fengtang Yang; Sanger Mouse Genetics Project; Ramiro Ramirez-Solis, Jeanne Esta