日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer

TRAILR2/CDH3 双特异性抗体在 CDH3 阳性胰腺癌中表现出选择性凋亡和肿瘤消退

Peter Jung, Stefan P Glaser, Jing Han, Alexandra Popa, Laura Pisarsky, Ningping Feng, Antonia Geyer, Franziska Haderk, Donat Alpar, Christopher Bristow, Susanne Schmittner, Paula-Elena Traexler, Mikhila Mahendra, Birgit Poehn, Poojabahen Gandhi, Roberto Fiorelli, Sanket Awate, Nicole Budano, Florian

WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells

WRN 解旋酶保护 BRCA2 突变癌细胞中脱保护的复制叉

Arindam Datta, Kajal Biswas, Joshua A Sommers, Haley Thompson, Sanket Awate, Claudia M Nicolae, Tanay Thakar, George-Lucian Moldovan, Robert H Shoemaker, Shyam K Sharan, Robert M Brosh Jr

FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links

FANCJ 弥补 RAP80 缺陷,抑制链间交联引起的基因组不稳定性

Sanket Awate, Joshua A Sommers, Arindam Datta, Sumeet Nayak, Marina A Bellani, Olivia Yang, Christopher A Dunn, Claudia M Nicolae, George-Lucian Moldovan, Michael M Seidman, Sharon B Cantor, Robert M Brosh

TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint

TLK1B 介导的 Rad9 磷酸化调节其核/细胞质定位和细胞周期检查点

Sanket Awate, Arrigo De Benedetti

Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy

TLK 的吩噻嗪抑制剂影响双链断裂修复和 DNA 损伤反应恢复,并通过放射模拟疗法增强肿瘤杀伤作用

Sharon Ronald, Sanket Awate, Abhijit Rath, Jennifer Carroll, Floyd Galiano, Donard Dwyer, Heather Kleiner-Hancock, J Michael Mathis, Simone Vigod, Arrigo De Benedetti