文献库，生知库 | 链接生命科学的每一步

Kollori Dhar # ，Kautilya Kumar Jena # ，Subhash Mehto ，Rinku Sahu ，Krushna C Murmu ，Atharva Anand Mahajan ，Sibaram Behera ，Ravi Kiran Putchala ，Reuben Jacob Mathew ，Ramyasingh Bal ，Soumya Kundu ，Santosh Kumar Das ，Swati Chauhan ，Sameekshya Satapathy ，Rina Yadav ，Swatismita Priyadarsini ，Khyathi Ratna Padala ，Prashanth Namdigalla ，Sanchita Mishra ，Prerana Muralidhara ，Kushagra Bansal ，Kesavardhana Sannula ，Punit Prasad ，Kiran Kumar Bokara ，Divya Tej Sowpati ，Anindya Ghosh-Roy ，Pravati Kumari Mahapatra ，Rohan Jayant Khadilkar ，Ramesh Yelagandula ，Santosh Chauhan

细胞生物学

发育与干细胞

发表日期：2025

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Bat adaptations in inflammation and cell death regulation contribute to viral tolerance

蝙蝠在炎症和细胞死亡调控方面的适应性有助于其对病毒的耐受性。

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.03204-23

Das, Subham; Jain, Disha; Chaudhary, Priyansh; Quintela-Tizon, Rita M; Banerjee, Arinjay; Kesavardhana, Sannula

Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potential

解码2.3.4.4b H5N1病毒的非人类哺乳动物适应性特征，以评估其对人类的适应潜力

期刊:Microbiology Spectrum

影响因子:3.8

doi:10.1128/spectrum.00948-25

Nataraj, Ranjana; Ashok, Avinash Karkada; Dey, Ayushi Amin; Kesavardhana, Sannula

微生物学

发表日期：2025

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Protocol for the detection of RHIM-protein oligomeric complex formation using DSP-mediated crosslinking in HEK293T cultured cells

利用DSP介导的交联检测HEK293T培养细胞中RHIM-蛋白寡聚复合物形成的实验方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2025.104190

Mishra, Sanchita; Dey, Ayushi Amin; Kesavardhana, Sannula

细胞生物学

发表日期：2025

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Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

蝙蝠 RNA 病毒利用病毒 RHIM 调控与 Z-RNA 传感和 ZBP1-RIPK3 信号传导相关的物种特异性细胞死亡程序

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2024.111444

Sanchita Mishra, Disha Jain, Ayushi Amin Dey, Sahana Nagaraja, Mansi Srivastava, Oyahida Khatun, Keerthana Balamurugan, Micky Anand, Avinash Karkada Ashok, Shashank Tripathi, Mahipal Ganji, Sannula Kesavardhana

PANoptosis Regulation in Reservoir Hosts of Zoonotic Viruses

人畜共患病毒宿主细胞凋亡调控

期刊:Viruses-Basel

影响因子:3.5

doi:10.3390/v16111733

Chandra, Anantika; Kesavardhana, Sannula

Emerging Role of ZBP1 in Z-RNA Sensing, Influenza Virus-Induced Cell Death, and Pulmonary Inflammation

ZBP1在Z-RNA感知、流感病毒诱导的细胞死亡和肺部炎症中的新兴作用

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.00401-22

Basavaraju, Sharath; Mishra, Sanchita; Jindal, Rashi; Kesavardhana, Sannula

肺炎

炎症

炎症/感染

Immunology/Inflammation

Inflammasome regulation in driving COVID-19 severity in humans and immune tolerance in bats

炎症小体调控在驱动人类 COVID-19 严重程度和蝙蝠免疫耐受中的作用

期刊:Journal of Leukocyte Biology

影响因子:3.1

doi:10.1002/JLB.4COVHR0221-093RR

Nagaraja, Sahana; Jain, Disha; Kesavardhana, Sannula

DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response

DDX3X 通过激活 NLRP3 炎症小体和 I 型干扰素反应来协调宿主对流感病毒的防御

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1016/j.jbc.2021.100579

Sannula Kesavardhana, Parimal Samir, Min Zheng, R K Subbarao Malireddi, Rajendra Karki, Bhesh Raj Sharma, David E Place, Benoit Briard, Peter Vogel, Thirumala-Devi Kanneganti

Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection

前沿：Caspase-8 是 Caspase-3 和 Gasdermin D 激活的关键，可控制甲型流感病毒感染期间的细胞死亡、细胞因子释放和宿主防御

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.2100757

Yaqiu Wang, Rajendra Karki, Min Zheng, Balabhaskararao Kancharana, SangJoon Lee, Sannula Kesavardhana, Baranda S Hansen, Shondra M Pruett-Miller, Thirumala-Devi Kanneganti

Programmed cell revival from imminent cell death enhances tissue repair and regeneration

程序性细胞复苏能够促进组织修复和再生，使细胞从即将死亡的状态中恢复过来。

Bat adaptations in inflammation and cell death regulation contribute to viral tolerance

蝙蝠在炎症和细胞死亡调控方面的适应性有助于其对病毒的耐受性。

Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potential

解码2.3.4.4b H5N1病毒的非人类哺乳动物适应性特征，以评估其对人类的适应潜力

Protocol for the detection of RHIM-protein oligomeric complex formation using DSP-mediated crosslinking in HEK293T cultured cells

利用DSP介导的交联检测HEK293T培养细胞中RHIM-蛋白寡聚复合物形成的实验方案

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

蝙蝠 RNA 病毒利用病毒 RHIM 调控与 Z-RNA 传感和 ZBP1-RIPK3 信号传导相关的物种特异性细胞死亡程序

PANoptosis Regulation in Reservoir Hosts of Zoonotic Viruses

人畜共患病毒宿主细胞凋亡调控

Emerging Role of ZBP1 in Z-RNA Sensing, Influenza Virus-Induced Cell Death, and Pulmonary Inflammation

ZBP1在Z-RNA感知、流感病毒诱导的细胞死亡和肺部炎症中的新兴作用

Inflammasome regulation in driving COVID-19 severity in humans and immune tolerance in bats

炎症小体调控在驱动人类 COVID-19 严重程度和蝙蝠免疫耐受中的作用

DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response

DDX3X 通过激活 NLRP3 炎症小体和 I 型干扰素反应来协调宿主对流感病毒的防御

Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection

前沿：Caspase-8 是 Caspase-3 和 Gasdermin D 激活的关键，可控制甲型流感病毒感染期间的细胞死亡、细胞因子释放和宿主防御