Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease.
ADAMTS4 对软骨寡聚基质蛋白 (COMP) 的切割产生了一种与骨关节炎和其他形式的退行性关节疾病相关的新表位
期刊:Matrix Biology
影响因子:4.8
doi:10.1016/j.matbio.2024.12.005
de Groot Rens, Folgado Patricia BadÃa, Yamamoto Kazuhiro, Martin Daniel R, Koch Christopher D, Debruin Danielle, Blagg Sophie, Minns Alexander F, Bhutada Sumit, Ahnström Josefin, Larkin Jonathan, Aspberg Anders, Ãnnerfjord Patrik, Apte Suneel S, Santamaria Salvatore
