Large scale quantification of natural killer cell-induced apoptosis in patient-derived organoids reveals intratumoral response heterogeneity.
对患者来源的类器官中自然杀伤细胞诱导的细胞凋亡进行大规模定量分析，揭示了肿瘤内反应的异质性。
期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-025-01251-7
Mercadante Marisa, Scheben Armin, Estrada Jacob, Savas-Carstens Jan, Sullivan William, Housel Nicholas, Sapar Maria, Volpari Tatiana, Hebner Jax, Rusielewicz Tomasz, Monsma Frederick J Jr, Semrau Stefan, Wang Yinan, Martin Laura A
肿瘤
凋亡
表观遗传
肿瘤免疫
自然杀伤细胞
细胞生物学
3D/类器官
