日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of AMPA receptors (AMPARs) containing transmembrane AMPAR regulatory protein γ-8 with JNJ-55511118 shows preclinical efficacy in reducing chronic repetitive alcohol self-administration

使用 JNJ-55511118 抑制含有跨膜 AMPAR 调节蛋白 γ-8 的 AMPA 受体 (AMPAR),在减少慢性重复性自我饮酒方面显示出临床前疗效

Jessica L Hoffman, Sara Faccidomo, Briana L Saunders, Seth M Taylor, Michelle Kim, Clyde W Hodge

Pharmacological inhibition of glycogen synthase kinase 3 increases operant alcohol self-administration in a manner associated with altered pGSK-3β, protein interacting with C kinase and GluA2 protein expression in the reward pathway of male C57BL/6J mice

糖原合酶激酶 3 的药理学抑制会增加操作性酒精自我给药,其方式与雄性 C57BL/6J 小鼠奖赏通路中 pGSK-3β、与 C 激酶相互作用的蛋白质和 GluA2 蛋白质表达改变有关

Sara Faccidomo, Sarah E Holstein, Taruni S Santanam, Briana L Saunders, Katarina S Swaim, Grant T Reid, Conor O'Neill, Vallari R Eastman, Clyde W Hodge

Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease

饮酒会加剧阿尔茨海默病 3xTg-AD 小鼠模型的神经和行为病理

Jessica L Hoffman, Sara Faccidomo, Michelle Kim, Seth M Taylor, Abigail E Agoglia, Ashley M May, Evan N Smith, L C Wong, Clyde W Hodge

Mining the nucleus accumbens proteome for novel targets of alcohol self-administration in male C57BL/6J mice

挖掘伏隔核蛋白质组以寻找雄性 C57BL/6J 小鼠自我饮酒的新靶点

Sara Faccidomo, Katarina S Swaim, Briana L Saunders, Taruni S Santanam, Seth M Taylor, Michelle Kim, Grant T Reid, Vallari R Eastman, Clyde W Hodge

Increased operant responding for ethanol in male C57BL/6J mice: specific regulation by the ERK1/2, but not JNK, MAP kinase pathway

雄性 C57BL/6J 小鼠对乙醇的操作性反应增强:由 ERK1/2 而非 JNK、MAP 激酶通路进行特异性调节

Sara Faccidomo, Joyce Besheer, P Crystal Stanford, Clyde W Hodge

Glutamatergic and GABAergic modulations of ultrasonic vocalizations during maternal separation distress in mouse pups

小鼠幼崽在母子分离痛苦期间,谷氨酸能和 GABA 能对超声波发声的调节

Aki Takahashi, Jasmine J Yap, Dawnya Zitzman Bohager, Sara Faccidomo, Terry Clayton, James M Cook, Klaus A Miczek