Sarah Dimeloe相关文献与解析，生知库 | 链接生命科学的每一步

Megan R Teh ，Nancy Gudgeon ，Joe N Frost ，Linda V Sinclair ，Alastair L Smith ，Christopher L Millington ，Barbara Kronsteiner ，Jennie Roberts ，Bryan P Marzullo ，Hannah Murray ，Alexandra E Preston ，Victoria Stavrou ，Jan Rehwinkel ，Thomas A Milne ，Daniel A Tennant ，Susanna J Dunachie ，Andrew E Armitage ，Sarah Dimeloe # ，Hal Drakesmith #

细胞生物学

T细胞

CD8

T细胞

发表日期：2025

文献求助收藏

Proteomic analysis reveals dysregulation of peripheral blood neutrophils in patients with Multiple Sclerosis

蛋白质组学分析揭示多发性硬化症患者外周血中性粒细胞功能失调

期刊:Clinical and Experimental Immunology

影响因子:3.4

doi:10.1093/cei/uxae115

Katie J Smith ，Zachary Lim ，Sonja Vermeren ，Veronique E Miron ，Sarah Dimeloe ，Donald J Davidson ，Anna Williams ，Emily Gwyer Findlay

Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

沙门氏菌癌症疗法通过代谢方式破坏肿瘤，但代价是损害T细胞免疫力。

期刊:EMBO Molecular Medicine

影响因子:9

doi:10.1038/s44321-024-00159-2

Alastair Copland,Gillian M Mackie,Lisa Scarfe,Elizabeth Jinks,David A J Lecky,Nancy Gudgeon,Riahne McQuade,Masahiro Ono,Manja Barthel,Wolf-Dietrich Hardt,Hiroshi Ohno,Wilma H M Hoevenaar,Sarah Dimeloe,David Bending,Kendle M Maslowski

Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma

骨髓中长链脂肪酸的摄取会抑制多发性骨髓瘤中 CD8+ T 细胞的代谢和功能。

期刊:Blood Advances

影响因子:7.4

doi:10.1182/bloodadvances.2023009890

Nancy Gudgeon ，Hannah Giles ，Emma L Bishop ，Taylor Fulton-Ward ，Cristina Escribano-Gonzalez ，Haydn Munford ，Anna James-Bott ，Kane Foster ，Farheen Karim ，Dedunu Jayawardana ，Ansar Mahmood ，Adam P Cribbs ，Daniel A Tennant ，Supratik Basu ，Guy Pratt ，Sarah Dimeloe

Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation

T细胞摄取琥珀酸会通过抑制线粒体葡萄糖氧化来抑制其效应功能。

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2022.111193

Nancy Gudgeon ，Haydn Munford ，Emma L Bishop ，James Hill ，Taylor Fulton-Ward ，David Bending ，Jennie Roberts ，Daniel A Tennant ，Sarah Dimeloe

1,25-Dihydroxyvitamin D3 suppresses CD4+ T-cell effector functionality by inhibition of glycolysis

1,25-二羟基维生素D3通过抑制糖酵解来抑制CD4+ T细胞的效应功能

期刊:Immunology

影响因子:4.9

doi:10.1111/imm.13472

Emma L Bishop ，Nancy H Gudgeon ，Gillian M Mackie ，Daniel Chauss ，Jennie Roberts ，Daniel A Tennant ，Kendle M Maslowski ，Behdad Afzali ，Martin Hewison ，Sarah Dimeloe

Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell

多组学分析将 mRNA 周转和谷氨酰胺代谢的翻译控制与活化 CD4+ T 细胞的分化结合起来

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-022-24132-6

Louise S Matheson, Georg Petkau, Beatriz Sáenz-Narciso, Vanessa D'Angeli, Jessica McHugh, Rebecca Newman, Haydn Munford, James West, Krishnendu Chakraborty, Jennie Roberts, Sebastian Łukasiak, Manuel D Díaz-Muñoz, Sarah E Bell, Sarah Dimeloe, Martin Turner

代谢

信号转导

T细胞

Translational Control

发表日期：2022

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The Induction of Alpha-1 Antitrypsin by Vitamin D in Human T Cells Is TGF-β Dependent: A Proposed Anti-inflammatory Role in Airway Disease

维生素 D 在人类 T 细胞中诱导 Alpha-1 抗胰蛋白酶依赖于 TGF-β：其在呼吸道疾病中发挥抗炎作用

期刊:Frontiers in Nutrition

影响因子:4

doi:10.3389/fnut.2021.667203

Yin-Huai Chen, Charlotte E Cheadle, Louise V Rice, Paul E Pfeffer, Sarah Dimeloe, Atul Gupta, Andrew Bush, Bibek Gooptu, Catherine M Hawrylowicz

Tolerogenic effects of 1,25-dihydroxyvitamin D on dendritic cells involve induction of fatty acid synthesis

1,25-二羟基维生素 D 对树突状细胞的耐受性作用涉及诱导脂肪酸合成

期刊:Journal of Steroid Biochemistry and Molecular Biology

影响因子:2.7

doi:10.1016/j.jsbmb.2021.105891

Amadeo Muñoz Garcia, Emma L Bishop, Danyang Li, Louisa E Jeffery, Antje Garten, Alpesh Thakker, Michelangelo Certo, Claudio Mauro, Daniel A Tennant, Sarah Dimeloe, Chris T Evelo, Susan L Coort, Martin Hewison

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells

白细胞渗出诱导的整合素信号通过LFA-1介导，诱导免疫细胞内源性补体C3表达，从而促进组织免疫。

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2020.02.006

Martin Kolev ，Erin E West ，Natalia Kunz ，Daniel Chauss ，E Ashley Moseman ，Jubayer Rahman ，Tilo Freiwald ，Maria L Balmer ，Jonas Lötscher ，Sarah Dimeloe ，Elizabeth C Rosser ，Lucy R Wedderburn ，Katrin D Mayer-Barber ，Andrea Bohrer ，Paul Lavender ，Andrew Cope ，Luopin Wang ，Mariana J Kaplan ，Niki M Moutsopoulos ，Dorian McGavern ，Steven M Holland ，Christoph Hess ，Majid Kazemian ，Behdad Afzali ，Claudia Kemper

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells

缺铁会导致CD8+ T细胞天冬氨酸敏感性功能障碍

Proteomic analysis reveals dysregulation of peripheral blood neutrophils in patients with Multiple Sclerosis

蛋白质组学分析揭示多发性硬化症患者外周血中性粒细胞功能失调

Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity

沙门氏菌癌症疗法通过代谢方式破坏肿瘤，但代价是损害T细胞免疫力。

Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma

骨髓中长链脂肪酸的摄取会抑制多发性骨髓瘤中 CD8+ T 细胞的代谢和功能。

Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation

T细胞摄取琥珀酸会通过抑制线粒体葡萄糖氧化来抑制其效应功能。

1,25-Dihydroxyvitamin D3 suppresses CD4+ T-cell effector functionality by inhibition of glycolysis

1,25-二羟基维生素D3通过抑制糖酵解来抑制CD4+ T细胞的效应功能

Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell

多组学分析将 mRNA 周转和谷氨酰胺代谢的翻译控制与活化 CD4+ T 细胞的分化结合起来

The Induction of Alpha-1 Antitrypsin by Vitamin D in Human T Cells Is TGF-β Dependent: A Proposed Anti-inflammatory Role in Airway Disease

维生素 D 在人类 T 细胞中诱导 Alpha-1 抗胰蛋白酶依赖于 TGF-β：其在呼吸道疾病中发挥抗炎作用

Tolerogenic effects of 1,25-dihydroxyvitamin D on dendritic cells involve induction of fatty acid synthesis

1,25-二羟基维生素 D 对树突状细胞的耐受性作用涉及诱导脂肪酸合成

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells

白细胞渗出诱导的整合素信号通过LFA-1介导，诱导免疫细胞内源性补体C3表达，从而促进组织免疫。