日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule

利用 G-四链体结合小分子靶向胰腺导管腺癌中的多种效应通路

Chiara Marchetti, Katherine G Zyner, Stephan A Ohnmacht, Mathew Robson, Shozeb M Haider, Jennifer P Morton, Giovanni Marsico, Tam Vo, Sarah Laughlin-Toth, Ahmed A Ahmed, Gloria Di Vita, Ingrida Pazitna, Mekala Gunaratnam, Rachael J Besser, Ana C G Andrade, Seckou Diocou, Jeremy A Pike, David Tannahi

DNA microstructure influences selective binding of small molecules designed to target mixed-site DNA sequences

DNA微结构影响针对混合位点DNA序列的小分子的选择性结合

Sarah Laughlin-Toth, E Kathleen Carter, Ivaylo Ivanov, W David Wilson

Modulation of topoisomerase IIα expression and chemosensitivity through targeted inhibition of NF-Y:DNA binding by a diamino p-anisyl-benzimidazole (Hx) polyamide

通过二氨基对甲氧基苯并咪唑 (Hx) 聚酰胺靶向抑制 NF-Y:DNA 结合来调节拓扑异构酶 IIα 表达和化学敏感性

Luke Pett, Konstantinos Kiakos, Vijay Satam, Pravin Patil, Sarah Laughlin-Toth, Matthew Gregory, Michael Bowerman, Kevin Olson, Mia Savagian, Megan Lee, Moses Lee, W David Wilson, Daniel Hochhauser, John A Hartley