日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications

工程改造 CAR-T 细胞用于成像和放射免疫治疗中的放射性半抗原捕获

Keifer Kurtz,Laura Eibler,Megan M Dacek,Lukas M Carter,Darren R Veach,Samantha Lovibond,Emma Reynaud,Sarah Qureshy,Michael R McDevitt,Christopher Bourne,Sebastien Monette,Blesida Punzalan,Shireen Khayat,Svena Verma,Adam L Kesner,Nai-Kong V Cheung,Heiko Schöder,Leah Gajecki,Sarah M Cheal,Steven M Larson,David A Scheinberg,Simone Krebs

A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy

用于治疗性两步预靶向放射免疫治疗的自组装和拆卸 (SADA) 双特异性抗体 (BsAb) 平台

Brian H Santich, Sarah M Cheal, Mahiuddin Ahmed, Michael R McDevitt, Ouathek Ouerfelli, Guangbin Yang, Darren R Veach, Edward K Fung, Mitesh Patel, Daniela Burnes Vargas, Aiza A Malik, Hong-Fen Guo, Pat B Zanzonico, Sebastien Monette, Adam O Michel, Charles M Rudin, Steven M Larson, Nai K Cheung

Theranostic pretargeted radioimmunotherapy of internalizing solid tumor antigens in human tumor xenografts in mice: Curative treatment of HER2-positive breast carcinoma

小鼠人类肿瘤异种移植中内化实体肿瘤抗原的诊断预定位放射免疫治疗:HER2 阳性乳腺癌的治愈性治疗

Sarah M Cheal, Hong Xu, Hong-Fen Guo, Mitesh Patel, Blesida Punzalan, Edward K Fung, Sang-Gyu Lee, Meghan Bell, Manisha Singh, Achim A Jungbluth, Pat B Zanzonico, Alessandra Piersigilli, Steven M Larson, Nai-Kong V Cheung

ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts

内源性和转染催乳素受体肿瘤异种移植的免疫 PET 成像

Sarah M Cheal, Shutian Ruan, Darren R Veach, Valerie A Longo, Blesida J Punzalan, Jiong Wu, Edward K Fung, Marcus P Kelly, Jessica R Kirshner, Jason T Giurleo, George Ehrlich, Amy Q Han, Gavin Thurston, William C Olson, Pat B Zanzonico, Steven M Larson, Jorge A Carrasquillo

Theranostic pretargeted radioimmunotherapy of colorectal cancer xenografts in mice using picomolar affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn binding scFv C825/GPA33 IgG bispecific immunoconjugates

使用皮摩尔亲和力 ⁸⁶Y 或 ¹⁷⁷Lu-DOTA-Bn 结合 scFv C825/GPA33 IgG 双特异性免疫缀合物对小鼠结肠直肠癌异种移植进行治疗性预定位放射免疫治疗

Sarah M Cheal, Hong Xu, Hong-Fen Guo, Sang-Gyu Lee, Blesida Punzalan, Sandhya Chalasani, Edward K Fung, Achim Jungbluth, Pat B Zanzonico, Jorge A Carrasquillo, Joseph O'Donoghue, Peter M Smith-Jones, K Dane Wittrup, Nai-Kong V Cheung, Steven M Larson2

Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3

人源化亲和力成熟的单克隆抗体 8H9 具有强效抗肿瘤活性并与肿瘤抗原 B7-H3 的 FG 环结合

Mahiuddin Ahmed, Ming Cheng, Qi Zhao, Yehuda Goldgur, Sarah M Cheal, Hong-fen Guo, Steven M Larson, Nai-kong V Cheung

STAQ: A route toward low power, multicolor nanoscopy

STAQ:迈向低功率、多色纳米显微技术之路

Tilman Rosales, Dan L Sackett, Jianhua Xu, Zhen-Dan Shi, Biying Xu, Haitao Li, Gurpreet Kaur, Erin Frohart, Nalini Shenoy, Sarah M Cheal, Haitao Wu, Andrés E Dulcey, Yulin Hu, Changhui Li, Kelly Lane, Gary L Griffiths, Jay R Knutson

Annotating STEAP1 regulation in prostate cancer with 89Zr immuno-PET

使用 89Zr 免疫 PET 注释前列腺癌中的 STEAP1 调控

Michael G Doran, Philip A Watson, Sarah M Cheal, Daniel E Spratt, John Wongvipat, Jeffrey M Steckler, Jorge A Carrasquillo, Michael J Evans, Jason S Lewis

Pairwise comparison of 89Zr- and 124I-labeled cG250 based on positron emission tomography imaging and nonlinear immunokinetic modeling: in vivo carbonic anhydrase IX receptor binding and internalization in mouse xenografts of clear-cell renal cell carcinoma

基于正电子发射断层扫描成像和非线性免疫动力学建模的 89Zr 和 124I 标记 cG250 的成对比较:小鼠透明细胞肾细胞癌异种移植中的体内碳酸酐酶 IX 受体结合和内化

Sarah M Cheal, Blesida Punzalan, Michael G Doran, Michael J Evans, Joseph R Osborne, Jason S Lewis, Pat Zanzonico, Steven M Larson

Preclinical evaluation of multistep targeting of diasialoganglioside GD2 using an IgG-scFv bispecific antibody with high affinity for GD2 and DOTA metal complex

使用对 GD2 和 DOTA 金属复合物具有高亲和力的 IgG-scFv 双特异性抗体对双脱唾液酸神经节苷脂 GD2 进行多步靶向临床前评估

Sarah M Cheal, Hong Xu, Hong-fen Guo, Pat B Zanzonico, Steven M Larson, Nai-Kong Cheung