日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

"They Call Us Amaphara (Junkies)": Intersectional Tuberculosis, Alcohol, and Drug Stigma in South Africa

“他们称我们为瘾君子(Amaphara)”:南非结核病、酒精和毒品交叉污名化

Carney, Tara; Mpisane, Noluthando; Magidson, Jessica F; Drainoni, Mari-Lynn; Niemand, Nandi; Weber, Sarah; Meade, Christina S; Jacobson, Karen R; Myers, Bronwyn

ChAdOx1-vectored Lassa fever vaccine elicits a robust cellular and humoral immune response and protects guinea pigs against lethal Lassa virus challenge

以ChAdOx1为载体的拉沙热疫苗可诱导强烈的细胞和体液免疫反应,并保护豚鼠免受致命性拉沙病毒攻击。

Fischer, Robert J; Purushotham, Jyothi N; van Doremalen, Neeltje; Sebastian, Sarah; Meade-White, Kimberly; Cordova, Kathleen; Letko, Michael; Jeremiah Matson, M; Feldmann, Friederike; Haddock, Elaine; LaCasse, Rachel; Saturday, Greg; Lambe, Teresa; Gilbert, Sarah C; Munster, Vincent J

External data required timely response by the Trial Steering-Data Monitoring Committee for the NALoxone InVEstigation (N-ALIVE) pilot trial

纳洛酮研究(N-ALIVE)试点试验的试验指导-数据监测委员会需要及时响应外部数据。

Bird, Sheila M; Strang, John; Ashby, Deborah; Podmore, John; Robertson, J Roy; Welch, Sarah; Meade, Angela M; Parmar, Mahesh K B

A brain-permeable small molecule reduces neuronal cholesterol by inhibiting activity of sirtuin 2 deacetylase

一种可渗透脑的小分子通过抑制 sirtuin 2 去乙酰化酶的活性来降低神经元胆固醇

David M Taylor, Uma Balabadra, Zhongmin Xiang, Ben Woodman, Sarah Meade, Allison Amore, Michele M Maxwell, Steven Reeves, Gillian P Bates, Ruth Luthi-Carter, Philip A S Lowden, Aleksey G Kazantsev

Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model

评估组蛋白去乙酰化酶作为亨廷顿氏病模型中的药物靶点。研究 R6/2 和 CAG140 敲入亨廷顿氏病小鼠模型和人类患者的脑组织以及神经元亨廷顿氏病细胞模型中的 HDAC

Luisa Quinti, Vanita Chopra, Dante Rotili, Sergio Valente, Allison Amore, Gianluigi Franci, Sarah Meade, Marta Valenza, Lucia Altucci, Michele M Maxwell, Elena Cattaneo, Steven Hersch, Antonello Mai, Aleksey Kazantsev

Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors

1,4-二氢吡啶结构支架的研究:新型 sirtuin 激活剂和抑制剂的发现

Antonello Mai, Sergio Valente, Sarah Meade, Vincenzo Carafa, Maria Tardugno, Angela Nebbioso, Andrea Galmozzi, Nico Mitro, Emma De Fabiani, Lucia Altucci, Aleksey Kazantsev