日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

G-quadruplexes associated with R-loops promote CTCF binding

与 R 环相关的 G-四链体促进 CTCF 结合

Phillip Wulfridge, Qingqing Yan, Nathaniel Rell, John Doherty, Skye Jacobson, Sarah Offley, Sandra Deliard, Kelly Feng, Jennifer E Phillips-Cremins, Alessandro Gardini, Kavitha Sarma

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

PP2A-Integrator-CDK9轴精细调控转录,可作为癌症治疗的靶点。

Stephin J Vervoort,Sarah A Welsh,Jennifer R Devlin,Elisa Barbieri,Deborah A Knight,Sarah Offley,Stefan Bjelosevic,Matteo Costacurta,Izabela Todorovski,Conor J Kearney,Jarrod J Sandow,Zheng Fan,Benjamin Blyth,Victoria McLeod,Joseph H A Vissers,Karolina Pavic,Ben P Martin,Gareth Gregory,Elena Demosthenous,Magnus Zethoven,Isabella Y Kong,Edwin D Hawkins,Simon J Hogg,Madison J Kelly,Andrea Newbold,Kaylene J Simpson,Otto Kauko,Kieran F Harvey,Michael Ohlmeyer,Jukka Westermarck,Nathanael Gray,Alessandro Gardini,Ricky W Johnstone

Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders

在ARID1B相关神经发育障碍中,无法从ARID1A-BAF向ARID1B-BAF转换会损害多能性退出和向神经嵴形成分化的能力。

Luca Pagliaroli # ,Patrizia Porazzi # ,Alyxandra T Curtis ,Chiara Scopa ,Harald M M Mikkers ,Christian Freund ,Lucia Daxinger ,Sandra Deliard ,Sarah A Welsh ,Sarah Offley ,Connor A Ott ,Bruno Calabretta ,Samantha A Brugmann ,Gijs W E Santen ,Marco Trizzino