日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Safety, tolerability, immunogenicity, and efficacy of ABvac40 active immunotherapy against Aβ40 in patients with mild cognitive impairment or very mild Alzheimer's disease: A randomized, double-blind, placebo-controlled phase 2 study

ABvac40 主动免疫疗法治疗轻度认知障碍或极轻度阿尔茨海默病患者的安全性、耐受性、免疫原性和疗效：一项随机、双盲、安慰剂对照的 II 期研究

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.70776
Pascual-Lucas, María; Lacosta, Ana María; Montañés, María; Canudas, Jesús; Loscos, Jorge; Monleón, Inmaculada; Allué, José Antonio; Sarasa, Leticia; Fandos, Noelia; Romero, Judith; Sarasa, Manuel; Torres, Mireia; Whyms, Dermot; Terencio, Jose; Piñol-Ripoll, Gerard; Boada, Mercè
阿尔茨海默症
神经科学
免疫/内分泌
发表日期：2025
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Longitudinal evaluation of the natural history of amyloid-β in plasma and brain

对血浆和脑组织中β-淀粉样蛋白自然史的纵向评估

期刊:Brain Communications
影响因子:4.5
doi:10.1093/braincomms/fcaa041
Burnham, Samantha C; Fandos, Noelia; Fowler, Christopher; Pérez-Grijalba, Virginia; Dore, Vincent; Doecke, James D; Shishegar, Rosita; Cox, Timothy; Fripp, Jurgen; Rowe, Christopher; Sarasa, Manuel; Masters, Colin L; Pesini, Pedro; Villemagne, Victor L
神经科学
发表日期：2020
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Plasma Aβ42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study

血浆Aβ42/40比值单独或与FDG-PET联合检测可准确预测淀粉样蛋白PET阳性：AB255研究的横断面分析

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-019-0549-1
Pérez-Grijalba, Virginia; Arbizu, Javier; Romero, Judith; Prieto, Elena; Pesini, Pedro; Sarasa, Leticia; Guillen, Fernando; Monleón, Inmaculada; San-José, Itziar; Martínez-Lage, Pablo; Munuera, Josep; Hernández, Isabel; Buendía, Mar; Sotolongo-Grau, Oscar; Alegret, Montserrat; Ruiz, Agustín; Tárraga, Lluis; Boada, Mercè; Sarasa, Manuel
发表日期：2019
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Safety, tolerability and immunogenicity of an active anti-Aβ(40) vaccine (ABvac40) in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase I trial

一项随机、双盲、安慰剂对照的I期临床试验，评估了活性抗Aβ(40)疫苗（ABvac40）在阿尔茨海默病患者中的安全性、耐受性和免疫原性。

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-018-0340-8
Lacosta, Ana-María; Pascual-Lucas, María; Pesini, Pedro; Casabona, Diego; Pérez-Grijalba, Virginia; Marcos-Campos, Iván; Sarasa, Leticia; Canudas, Jesus; Badi, Hassnae; Monleón, Inmaculada; San-José, Itziar; Munuera, Josep; Rodríguez-Gómez, Octavio; Abdelnour, Carla; Lafuente, Asunción; Buendía, Mar; Boada, Mercè; Tárraga, Lluis; Ruiz, Agustín; Sarasa, Manuel
阿尔茨海默症
免疫/内分泌
发表日期：2018
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Blood Markers in Healthy-Aged Nonagenarians: A Combination of High Telomere Length and Low Amyloidβ Are Strongly Associated With Healthy Aging in the Oldest Old

健康九十岁以上老人的血液标志物：端粒长度长和β-淀粉样蛋白水平低的组合与高龄老人的健康衰老密切相关

期刊:Frontiers in Aging Neuroscience
影响因子:4.5
doi:10.3389/fnagi.2018.00380
Fernández-Eulate, Gorka; Alberro, Ainhoa; Muñoz-Culla, Maider; Zulaica, Miren; Zufiría, Mónica; Barandiarán, Myriam; Etxeberria, Igone; Yanguas, José Javier; Gallardo, Maria Mercedes; Soberón, Nora; Lacosta, Ana María; Pérez-Grijalba, Virginia; Canudas, Jesús; Fandos, Noelia; Pesini, Pedro; Sarasa, Manuel; Indakoetxea, Begoña; Moreno, Fermin; Vergara, Itziar; Otaegui, David; Blasco, Maria; López de Munain, Adolfo
衰老
发表日期：2018
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Cognitive Composites Domain Scores Related to Neuroimaging Biomarkers within Probable-Amnestic Mild Cognitive Impairment-Storage Subtype

认知综合领域评分与可能遗忘型轻度认知障碍-储存亚型中的神经影像生物标志物相关

期刊:Journal of Alzheimers Disease
影响因子:3.1
doi:10.3233/JAD-161223
Espinosa, Ana; Alegret, Montserrat; Pesini, Pedro; Valero, Sergi; Lafuente, Asunción; Buendía, Mar; San José, Itziar; Ibarria, Marta; Tejero, Miguel A; Giménez, Joan; Ruiz, Susana; Hernández, Isabel; Pujadas, Francesc; Martínez-Lage, Pablo; Munuera, Josep; Arbizu, Javier; Tárraga, Lluis; Hendrix, Suzanne B; Ruiz, Agustín; Becker, James T; Landau, Susan M; Sotolongo-Grau, Oscar; Sarasa, Manuel; Boada, Mercè
神经科学
发表日期：2017
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Validation of Immunoassay-Based Tools for the Comprehensive Quantification of Aβ40 and Aβ42 Peptides in Plasma

验证基于免疫分析的血浆中Aβ40和Aβ42肽段全面定量检测工具

期刊:Journal of Alzheimers Disease
影响因子:3.1
doi:10.3233/JAD-160325
Pérez-Grijalba, Virginia; Fandos, Noelia; Canudas, Jesús; Insua, Daniel; Casabona, Diego; Lacosta, Ana M; Montañés, María; Pesini, Pedro; Sarasa, Manuel
免疫/内分泌
发表日期：2016
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Association between cell-bound blood amyloid-β(1-40) levels and hippocampus volume

细胞结合血液淀粉样蛋白β(1-40)水平与海马体积之间的关联

期刊:Alzheimers Research & Therapy
影响因子:7.6
doi:10.1186/s13195-014-0056-3
Sotolongo-Grau, Oscar; Pesini, Pedro; Valero, Sergi; Lafuente, Asunción; Buendía, Mar; Pérez-Grijalba, Virginia; José, Itziar San; Ibarria, Marta; Tejero, Miguel A; Giménez, Joan; Hernández, Isabel; Tárraga, Lluís; Ruiz, Agustín; Boada, Mercé; Sarasa, Manuel
细胞生物学
发表日期：2014
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Neprilysin is poorly expressed in the prefrontal cortex of aged dogs with cognitive dysfunction syndrome

脑啡肽酶在患有认知功能障碍综合征的老年犬的前额皮质中表达不足

期刊:International Journal of Alzheimer's Disease
影响因子:
doi:10.1155/2014/483281
Canudas, Jesús; Insua, Daniel; Sarasa, Leticia; González-Martínez, Angela; Suárez, María Luisa; Santamarina, Germán; Pesini, Pedro; Sarasa, Manuel
神经科学
发表日期：2014
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Reliable Measurements of the β-Amyloid Pool in Blood Could Help in the Early Diagnosis of AD

可靠测量血液中β-淀粉样蛋白池水平可能有助于阿尔茨海默病的早期诊断。

期刊:International Journal of Alzheimer's Disease
影响因子:
doi:10.1155/2012/604141
Pesini, Pedro; Pérez-Grijalba, Virginia; Monleón, Inmaculada; Boada, Mercè; Tárraga, Lluís; Martínez-Lage, Pablo; San-José, Itziar; Sarasa, Manuel
阿尔茨海默症
发表日期：2012
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